{"id":"W2093295909","doi":"10.1038/cddis.2015.36","title":"Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":214,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; University of Manitoba; Children's Hospital Research Institute of Manitoba; Research Manitoba","funders":"Canadian Institutes of Health Research; University of Manitoba; Research Manitoba; University of Calgary; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Myofibroblast; Regulator; Transforming growth factor; Cell biology; Cancer research; Fibrosis; Biology; Chemistry; Medicine; Pathology; Biochemistry; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001161823,0.0002018915,0.0003889588,0.0001456153,0.00004259348,0.00001320769,0.00008432184,0.00009911366,0.0001250378],"category_scores_gemma":[0.0000483043,0.0001805764,0.0001940166,0.0001562926,0.0000594152,0.00008629264,0.0000548296,0.0000745287,0.00001850182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006203962,"about_ca_system_score_gemma":0.0006104113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004597467,"about_ca_topic_score_gemma":7.737873e-7,"domain_scores_codex":[0.9987119,0.00005081002,0.0003318553,0.0003408394,0.0002970862,0.0002674914],"domain_scores_gemma":[0.9981729,0.0000269669,0.00009715057,0.0004008767,0.00006986745,0.001232244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03207372,0.004820289,0.6538185,0.004477544,0.0005748765,0.002872881,0.004160086,0.00004522947,0.2673916,0.002394621,0.0144621,0.01290853],"study_design_scores_gemma":[0.02478265,0.001144968,0.884177,0.0003406353,0.0006788534,0.00001383325,0.0001607675,0.0003797477,0.08023408,0.006377043,0.001125351,0.0005850744],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924842,0.00512829,0.00000601528,0.0001162717,0.00008188342,0.0004114156,0.00004139855,0.0000506812,0.001679856],"genre_scores_gemma":[0.9981052,0.00005534844,0.0001180877,0.0005985218,0.0002218179,0.00001423096,0.00005900518,0.00002892542,0.0007988065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2303585,"threshold_uncertainty_score":0.7363691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02845373801933513,"score_gpt":0.2791710123957052,"score_spread":0.25071727437637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}