{"id":"W2093296978","doi":"10.1039/c4ob01441c","title":"E. coli cells expressing the Baeyer–Villiger monooxygenase ‘MO14’ (ro03437) from Rhodococcus jostii RHA1 catalyse the gram-scale resolution of a bicyclic ketone in a fermentor","year":2014,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Optech (Canada)","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Ketone; Chemistry; Bicyclic molecule; Rhodococcus; Stereochemistry; Gram; Organic chemistry; Bacteria; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000425723,0.0002874045,0.000262885,0.00003231768,0.000122988,0.00004520212,0.0004604952,0.0002550892,0.0000290727],"category_scores_gemma":[0.0001663495,0.000207222,0.0001523256,0.0003310539,0.0001952476,0.000006677456,0.0001938059,0.0002127682,0.00001402447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004168742,"about_ca_system_score_gemma":0.00006833093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002616553,"about_ca_topic_score_gemma":0.00002918449,"domain_scores_codex":[0.9983205,0.0001273715,0.0004144401,0.0005658971,0.0002046538,0.0003671198],"domain_scores_gemma":[0.9986022,0.00001452611,0.0001950658,0.00102443,0.00007704639,0.00008675643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005306572,0.00009931088,0.00005599911,0.00004586071,0.00005312327,0.000002328881,0.0001476558,0.00003100202,0.9985983,0.000001479822,0.0004212577,0.0004905722],"study_design_scores_gemma":[0.0004950679,0.00003255555,0.0005065086,0.00005324542,0.00006414359,0.00001362439,0.0001167518,0.0001900693,0.9881221,0.00002181843,0.010135,0.0002491265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760096,0.001471152,0.0215749,0.0003116981,0.0001945939,0.000261139,0.00004856498,0.00002419422,0.0001041399],"genre_scores_gemma":[0.9982814,0.0001697905,0.0003883783,0.0001169786,0.000432132,0.00002942292,0.0002117447,0.00004683367,0.0003233833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02227172,"threshold_uncertainty_score":0.8450267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003948055018394031,"score_gpt":0.196558108460064,"score_spread":0.1926100534416699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}