{"id":"W2093360791","doi":"10.1016/j.vaccine.2012.10.076","title":"Safety and immunogenicity of pneumococcal protein vaccine candidates: Monovalent choline-binding protein A (PcpA) vaccine and bivalent PcpA–pneumococcal histidine triad protein D vaccine","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi Pasteur","keywords":"Immunogenicity; Medicine; Streptococcus pneumoniae; Immunology; Discontinuation; Adverse effect; Pneumococcal vaccine; Pneumococcal infections; Antibody; Internal medicine; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001343687,0.000338976,0.0003122733,0.0002724664,0.0002205489,0.0004057383,0.0002843384,0.0006637584,0.001104792],"category_scores_gemma":[0.001852612,0.0001453482,0.000359268,0.0001740441,0.0003455276,0.0003823905,0.0002038254,0.0006284108,0.000299843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005031675,"about_ca_system_score_gemma":0.0005195527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00106082,"about_ca_topic_score_gemma":0.0004604852,"domain_scores_codex":[0.9993345,0.0001930505,0.00005169982,0.00006714078,0.0002704723,0.00008316944],"domain_scores_gemma":[0.999009,0.000274152,0.0002280499,0.00008511174,0.0002791811,0.0001244985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.06396499,0.005072345,0.1225237,0.0005795626,0.0005265802,0.0008752859,0.0004315323,0.003830911,0.662488,0.0007511476,0.001273146,0.1376829],"study_design_scores_gemma":[0.002612846,0.1421334,0.2863665,0.00008269008,0.001044412,0.004369655,0.0003966903,0.008546728,0.5451183,0.0009147561,0.00836278,0.00005126785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969376,0.001505145,0.0005030183,0.0001300905,0.00002897913,0.00002098906,0.0001129844,0.000007077355,0.0007540163],"genre_scores_gemma":[0.9989784,0.0002318133,0.00009222549,0.00004786193,0.00002189915,0.000007624205,0.0001917273,0.000002127685,0.0004264336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001343687,"threshold_uncertainty_score":0.007106185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01632914479994807,"score_gpt":0.2670501649472132,"score_spread":0.2507210201472652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}