{"id":"W2093360791","doi":"10.1016/j.vaccine.2012.10.076","title":"Safety and immunogenicity of pneumococcal protein vaccine candidates: Monovalent choline-binding protein A (PcpA) vaccine and bivalent PcpA–pneumococcal histidine triad protein D vaccine","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi Pasteur","keywords":"Immunogenicity; Medicine; Streptococcus pneumoniae; Immunology; Discontinuation; Adverse effect; Pneumococcal vaccine; Pneumococcal infections; Antibody; Internal medicine; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001845699,0.001276038,0.00243746,0.001064019,0.0006040283,0.00007233831,0.0003769879,0.0006075461,0.0006799564],"category_scores_gemma":[0.0007712824,0.001030382,0.0004218066,0.001396711,0.00005636587,0.0006499261,0.0005723719,0.001332765,0.00005831873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004953997,"about_ca_system_score_gemma":0.0003047952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003409288,"about_ca_topic_score_gemma":0.0001272112,"domain_scores_codex":[0.9932607,0.0004028331,0.002582886,0.001303037,0.0007794803,0.001671109],"domain_scores_gemma":[0.9956582,0.0001588275,0.001059701,0.00135786,0.0005131436,0.001252315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00499454,0.001644003,0.07129589,0.001295751,0.0005699502,0.00005858521,0.0002495887,0.000005675281,0.9158586,0.0002345376,0.0001219232,0.003670968],"study_design_scores_gemma":[0.04245571,0.005409041,0.5089582,0.002905829,0.001418464,0.001560626,0.0002466299,0.0006322233,0.3906845,0.00009257944,0.04365372,0.001982508],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814762,0.003306909,0.0002429387,0.005335052,0.0003274415,0.008547285,0.0002004695,0.0003441727,0.0002195231],"genre_scores_gemma":[0.9936724,0.0006278176,0.0005252436,0.0001310649,0.000992022,0.0009129519,0.0001624805,0.0002064601,0.002769581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5251741,"threshold_uncertainty_score":0.9999992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01632914479994807,"score_gpt":0.2670501649472132,"score_spread":0.2507210201472652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}