{"id":"W2093365663","doi":"10.1016/j.imlet.2012.01.001","title":"A specific type of membrane microdomains is involved in the maintenance and translocation of kinase active Lck to lipid rafts","year":2012,"lang":"en","type":"article","venue":"Immunology Letters","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; Akademie Věd České Republiky; Grantová Agentura České Republiky","keywords":"Lipid raft; Cell biology; Compartmentalization (fire protection); Phosphorylation; T-cell receptor; Tyrosine phosphorylation; T cell; Chromosomal translocation; Chemistry; Lipid microdomain; Signal transduction; Biology; Biochemistry; Membrane; Immunology; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000391589,0.0002248083,0.0004715832,0.0002583613,0.00007685171,0.000003804198,0.0003961906,0.0002912659,0.0001329684],"category_scores_gemma":[0.00004718963,0.0001750794,0.0000796299,0.0003670734,0.0008753727,0.0001135178,0.0000753943,0.0004130948,0.0001091717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003988916,"about_ca_system_score_gemma":0.00002825044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002211115,"about_ca_topic_score_gemma":0.00003461561,"domain_scores_codex":[0.998224,0.0004560237,0.0004635583,0.0002840286,0.00003719281,0.0005351528],"domain_scores_gemma":[0.9989786,0.0002668941,0.000200012,0.0004696235,0.00006877951,0.00001606991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009964353,0.0002789259,0.003034065,0.00002212335,0.0001963185,0.000002997499,0.01078703,0.000001252203,0.9801144,0.0004250892,0.001805989,0.002335401],"study_design_scores_gemma":[0.001963075,0.0002692962,0.02180566,0.00005500654,0.00003319556,0.00006534791,0.001742163,2.406615e-7,0.9549335,0.00002229539,0.01893251,0.0001777003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866265,0.006563285,0.00007048168,0.005409885,0.0007526499,0.0004144426,0.0000242169,0.00001645147,0.0001220548],"genre_scores_gemma":[0.9968428,0.0008990658,0.0001290379,0.001927091,0.00002809015,0.00002759458,0.00003479165,0.00001721792,0.00009431027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02518086,"threshold_uncertainty_score":0.713953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783103353504593,"score_gpt":0.2300541101751993,"score_spread":0.2122230766401534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}