{"id":"W2093400276","doi":"10.1016/s0006-3495(03)74874-7","title":"Freezing of a Fish Antifreeze Protein Results in Amyloid Fibril Formation","year":2003,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institutes of Health Research; University of Alberta","funders":"","keywords":"Fibril; Amyloid (mycology); Chemistry; Antifreeze protein; Biophysics; Amyloid fibril; Chaotropic agent; Biochemistry; Amyloid β; Biology; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000194864,0.000401781,0.0003607367,0.0001509056,0.000238961,0.0002408614,0.0004138801,0.0004960021,0.00130278],"category_scores_gemma":[0.0002354241,0.0002210239,0.0006493714,0.0001167923,0.0004089539,0.0003094371,0.0002586604,0.0008680787,0.0003138928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005890502,"about_ca_system_score_gemma":0.0002052169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002366886,"about_ca_topic_score_gemma":0.002158077,"domain_scores_codex":[0.9999154,0.000006651587,0.000007463162,0.00001929615,0.00001858317,0.00003256655],"domain_scores_gemma":[0.9997087,0.00008412242,0.0000620436,0.00005688307,0.00002988835,0.00005820536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002908144,0.00002202135,0.0003935074,0.00002276697,0.0000185876,0.0001265822,0.0000270149,0.00008992436,0.9985544,0.00005498544,0.0000383059,0.0003610775],"study_design_scores_gemma":[0.00002084837,0.0002545013,0.00780381,0.000004241468,0.00002116231,0.000264894,0.00003153755,0.0007708613,0.9903939,0.00007305582,0.0003546332,0.00000653213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980651,0.0002671243,0.0008279869,0.00006190634,0.00002216986,0.00001158075,0.0001390619,0.00002411087,0.0005810648],"genre_scores_gemma":[0.996814,0.0001877234,0.0008372172,0.00008479953,0.00001068645,0.00001635958,0.0003888297,0.00004527513,0.001615143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002366886,"threshold_uncertainty_score":0.004706264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007815591837947758,"score_gpt":0.2301265512650374,"score_spread":0.2223109594270896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}