{"id":"W2093422837","doi":"10.1016/s0891-5849(02)00873-0","title":"Deferiprone protects against doxorubicin-induced myocyte cytotoxicity","year":2002,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Deferiprone; Doxorubicin; Chemistry; Xanthine oxidase; Dexrazoxane; Myocyte; Pharmacology; Semiquinone; Oxidative stress; Biochemistry; Deferoxamine; Anthracycline; Medicine; Internal medicine; Enzyme; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000411597,0.0002931615,0.0007318752,0.0001600697,0.0001904275,0.000005691772,0.0001412195,0.0005300702,0.0004685575],"category_scores_gemma":[0.0006844265,0.0002124872,0.0001027836,0.0003019882,0.000804257,0.00005896042,0.00005707589,0.0006406002,0.00003656719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008015944,"about_ca_system_score_gemma":0.00003708369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005122859,"about_ca_topic_score_gemma":0.00001081604,"domain_scores_codex":[0.9982512,0.0001276666,0.000405377,0.0005205691,0.0002299248,0.0004652601],"domain_scores_gemma":[0.9987249,0.0001351991,0.0001061437,0.0005002748,0.0000701117,0.0004633648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000241067,0.0001367611,0.0008211222,0.00008701595,0.000130328,0.00005920886,0.0003814901,1.235094e-7,0.9567987,0.00106446,0.002516864,0.03776284],"study_design_scores_gemma":[0.01641267,0.003563335,0.01181312,0.000571674,0.0002084069,0.0007551914,0.0001839505,0.0004555633,0.9271175,0.003236665,0.03514251,0.0005394313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722742,0.002536886,0.000532639,0.01265077,0.0002772505,0.0009330125,0.00001075526,0.0001788829,0.01060556],"genre_scores_gemma":[0.989226,0.00120402,0.0004219509,0.007438071,0.001136455,0.00005945149,0.00005583798,0.00002600959,0.0004322068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03722341,"threshold_uncertainty_score":0.8664975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03429963887493116,"score_gpt":0.2828689371393935,"score_spread":0.2485692982644624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}