{"id":"W2093432933","doi":"10.1016/j.jmb.2004.07.094","title":"Diversity in Structure and Function of the Ets Family PNT Domains","year":2004,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Domain (mathematical analysis); Genetics; Transcription factor; ETS transcription factor family; Biology; Protein structure; Nuclear magnetic resonance spectroscopy; Helix (gastropod); Function (biology); Protein domain; Structure function; Monomer; Computational biology; Chemistry; Crystallography; Stereochemistry; Gene; Biochemistry; Physics; Polymer; Mathematics; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001208221,0.00007296803,0.0001228898,0.0000581719,0.00005284428,0.0000020805,0.0001135581,0.0001817023,0.000001825127],"category_scores_gemma":[0.00003682938,0.00005322007,0.00007810392,0.00008820584,0.00009668159,0.000002758608,0.0002001959,0.0001206762,8.124351e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003249883,"about_ca_system_score_gemma":0.00007966895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002756203,"about_ca_topic_score_gemma":0.00006482341,"domain_scores_codex":[0.9994534,0.00007554652,0.0001985736,0.0001048746,0.00007648196,0.00009116192],"domain_scores_gemma":[0.9995448,0.000003901292,0.0002199231,0.0001247594,0.00007907479,0.0000275358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001345765,0.00001621074,0.01109986,0.000004735355,0.00005082892,0.000002429604,0.00004813143,0.002740812,0.9843839,0.0002291507,0.0000161441,0.001273167],"study_design_scores_gemma":[0.002126721,0.0007067579,0.3313093,0.00003194652,0.00005856615,0.0001178637,0.0000470675,0.000006143717,0.6574118,0.007073656,0.001004635,0.000105559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936289,0.00181024,0.003955486,0.0002552815,0.0002500761,0.00006802237,0.000005478772,7.514356e-7,0.0000257252],"genre_scores_gemma":[0.9993907,0.0001334166,0.0002611421,0.000138847,0.00006226131,2.481457e-7,0.000004245085,0.000004977659,0.000004204423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3269721,"threshold_uncertainty_score":0.2170251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005185727700530341,"score_gpt":0.2233843843430743,"score_spread":0.218198656642544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}