{"id":"W2093456571","doi":"10.1161/01.res.0000057386.15390.a3","title":"Differential Actions of PAR <sub>2</sub> and PAR <sub>1</sub> in Stimulating Human Endothelial Cell Exocytosis and Permeability","year":2003,"lang":"en","type":"article","venue":"Circulation Research","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"Kidney Foundation of Canada; Fondation pour la Recherche Médicale; Canadian Blood Services","keywords":"Exocytosis; RHOA; Heterotrimeric G protein; Cell biology; G protein; Adenylyl cyclase; Biology; Signal transduction; Chemistry; Endocrinology; Secretion","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000403016,0.0001419951,0.000187986,0.0001395733,0.0002490673,0.00004069473,0.00007577713,0.0001954837,0.00001750974],"category_scores_gemma":[0.0001681999,0.000142188,0.00005849841,0.0001658562,0.0002546058,0.0000137074,0.00007768289,0.0002409348,0.000001193284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000266772,"about_ca_system_score_gemma":0.00007968424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003576724,"about_ca_topic_score_gemma":0.0001129223,"domain_scores_codex":[0.9983529,0.0003204281,0.0002943481,0.0004426078,0.0002752869,0.0003144403],"domain_scores_gemma":[0.9993206,0.00006065209,0.00006393083,0.0002864133,0.0001603897,0.000107971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002868286,0.0000783084,0.1524907,0.00007283057,0.000008868444,0.000001020719,0.0001202358,0.00008230864,0.8454927,0.00003120041,0.000005708549,0.001587354],"study_design_scores_gemma":[0.0006591319,0.00007680592,0.3014466,0.00001006629,0.00001290814,0.000004004739,0.00006316126,0.00008056864,0.6974564,0.00007729261,0.00001706569,0.00009597596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991916,0.00004844039,0.00008032149,0.00001805374,0.00005675144,0.0003693877,0.00002272761,0.000006902414,0.0002058452],"genre_scores_gemma":[0.9996747,0.00006083917,0.00003064452,0.000006470676,0.0001095362,0.00003146106,0.00006109996,0.00001909314,0.000006122108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1489558,"threshold_uncertainty_score":0.5798259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04416157636897591,"score_gpt":0.3256175290510234,"score_spread":0.2814559526820475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}