{"id":"W2093456571","doi":"10.1161/01.res.0000057386.15390.a3","title":"Differential Actions of PAR <sub>2</sub> and PAR <sub>1</sub> in Stimulating Human Endothelial Cell Exocytosis and Permeability","year":2003,"lang":"en","type":"article","venue":"Circulation Research","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"Kidney Foundation of Canada; Fondation pour la Recherche Médicale; Canadian Blood Services","keywords":"Exocytosis; RHOA; Heterotrimeric G protein; Cell biology; G protein; Adenylyl cyclase; Biology; Signal transduction; Chemistry; Endocrinology; Secretion","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001951476,0.0002388485,0.0002859407,0.000109771,0.00008935479,0.0004004478,0.0001245346,0.0003066048,0.001540252],"category_scores_gemma":[0.0002122864,0.0001517578,0.0002922498,0.0001083115,0.0001408251,0.0003225847,0.0001730702,0.0004544498,0.000391982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000203081,"about_ca_system_score_gemma":0.000126128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001834376,"about_ca_topic_score_gemma":0.0001632057,"domain_scores_codex":[0.9997647,0.00005593738,0.00002407631,0.00003290145,0.00003642193,0.00008588716],"domain_scores_gemma":[0.999913,0.00002513017,0.00001502166,0.0000107095,0.000007583716,0.00002849305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001203351,0.00007301104,0.0003097687,0.00006511677,0.00001259849,0.0001078953,0.00002615263,0.00007266324,0.9956291,0.0002088649,0.00008957605,0.002201876],"study_design_scores_gemma":[0.0001126356,0.001038465,0.01357349,0.000006524027,0.00004261501,0.0006358789,0.0000569176,0.00117062,0.9809734,0.00007781391,0.002303411,0.000008243572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951864,0.001897268,0.001020942,0.00008703967,0.00003204668,0.00002531685,0.0002465579,0.00002280785,0.001481656],"genre_scores_gemma":[0.9956332,0.001159505,0.001465484,0.0001530154,0.00003947835,0.00006884726,0.0003564569,0.00001071747,0.001113174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001540252,"threshold_uncertainty_score":0.005152643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04416157636897591,"score_gpt":0.3256175290510234,"score_spread":0.2814559526820475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}