{"id":"W2093505571","doi":"10.1177/0748730405277232","title":"Differential Control of Bmal1 Circadian Transcription by REV-ERB and ROR Nuclear Receptors","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Rhythms","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":747,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; McGill University; Douglas Mental Health University Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale","keywords":"Biology; Circadian rhythm; Nuclear receptor; Transcription factor; Transcription (linguistics); Circadian clock; CLOCK; Gene; Cell biology; Genetics; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028882,0.000241228,0.0002496485,0.0003101675,0.000156116,0.0005302191,0.0002260211,0.0001478767,0.0009977521],"category_scores_gemma":[0.0003831747,0.0001356441,0.0002189482,0.0001347286,0.0002376867,0.0003119584,0.0003263179,0.0003414754,0.0004168057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004116905,"about_ca_system_score_gemma":0.0001876603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00046103,"about_ca_topic_score_gemma":0.001174528,"domain_scores_codex":[0.9995414,0.0001033523,0.00003009946,0.00008045353,0.00008738413,0.0001573852],"domain_scores_gemma":[0.9998145,0.00003480599,0.00005094658,0.00002601615,0.0000281975,0.00004567118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002617952,0.000009271307,0.0003763776,0.00002886358,0.00000400559,0.00004731436,0.00003257135,0.00003472768,0.9941679,0.0006547031,0.00006279814,0.004319618],"study_design_scores_gemma":[0.00009247045,0.0003341546,0.03471601,0.00003121627,0.00003633649,0.001060269,0.000279775,0.001543522,0.9460251,0.0009903025,0.01486201,0.00002886958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759371,0.01139636,0.00461431,0.0003588986,0.00008079891,0.00001940128,0.0002915908,0.000106388,0.00719512],"genre_scores_gemma":[0.9909956,0.002198438,0.002882747,0.0001230512,0.00002471751,0.00002537917,0.0002656912,0.00003836079,0.003446019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009977521,"threshold_uncertainty_score":0.003337801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02272012633441013,"score_gpt":0.2375333953819182,"score_spread":0.2148132690475081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}