{"id":"W2093554670","doi":"10.1021/cc050003d","title":"Deazapurine Solid-Phase Synthesis:  Combinatorial Synthesis of a Library of N3,N5,C6-Trisubstituted Pyrrolo[3,2-<i>d</i>]pyrimidine Derivatives on Cross-Linked Polystyrene Bearing a Cysteamine Linker","year":2005,"lang":"en","type":"article","venue":"Journal of Combinatorial Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Pyrimidine; Linker; Polystyrene; Solid-phase synthesis; Chemistry; Combinatorial chemistry; Bearing (navigation); Phase (matter); Cysteamine; Polymer chemistry; Stereochemistry; Organic chemistry; Computer science; Biochemistry; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001165277,0.0006552338,0.0004862839,0.0003986522,0.0001907071,0.0003453485,0.0004071122,0.0002895471,0.002193937],"category_scores_gemma":[0.0001161272,0.0002561437,0.0002812253,0.0005353882,0.0001270415,0.0002176166,0.0002980517,0.0004558073,0.001553484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003203578,"about_ca_system_score_gemma":0.0002924471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002657667,"about_ca_topic_score_gemma":0.001006792,"domain_scores_codex":[0.9998429,0.00001828763,0.00001110533,0.00004399192,0.00005232756,0.00003134841],"domain_scores_gemma":[0.9999177,0.00001253366,0.00001689353,0.00001360249,0.00001313347,0.00002607192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007199521,0.00007390081,0.00005456779,0.00007795355,0.000008258273,0.00005620753,0.00001190158,0.0005859786,0.9917195,0.0001935261,0.0001008,0.00704543],"study_design_scores_gemma":[0.00002361543,0.0003923413,0.000295357,0.000003016144,0.00001333799,0.0001142541,0.000004437539,0.0008794879,0.992045,0.00004510888,0.006176341,0.000007582129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9259102,0.003468081,0.04784913,0.0001033208,0.0001568419,0.001047489,0.003749619,0.001290224,0.01642499],"genre_scores_gemma":[0.9301536,0.002788131,0.04878774,0.0000886054,0.00004067878,0.0006291462,0.003915388,0.0001757993,0.01342093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002193937,"threshold_uncertainty_score":0.007339418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009022706772801621,"score_gpt":0.2831199598655521,"score_spread":0.2740972530927505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}