{"id":"W2093554670","doi":"10.1021/cc050003d","title":"Deazapurine Solid-Phase Synthesis:  Combinatorial Synthesis of a Library of N3,N5,C6-Trisubstituted Pyrrolo[3,2-<i>d</i>]pyrimidine Derivatives on Cross-Linked Polystyrene Bearing a Cysteamine Linker","year":2005,"lang":"en","type":"article","venue":"Journal of Combinatorial Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Pyrimidine; Linker; Polystyrene; Solid-phase synthesis; Chemistry; Combinatorial chemistry; Bearing (navigation); Phase (matter); Cysteamine; Polymer chemistry; Stereochemistry; Organic chemistry; Computer science; Biochemistry; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006122753,0.0005027408,0.001348534,0.0001520679,0.0001025587,0.00005931429,0.0008407311,0.0005911912,0.0001815666],"category_scores_gemma":[0.00230157,0.0004517859,0.0008770469,0.0003870289,0.0003478905,0.00006201897,0.0002542936,0.0004626361,0.000002325563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006887384,"about_ca_system_score_gemma":0.0003167112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009681436,"about_ca_topic_score_gemma":3.45368e-7,"domain_scores_codex":[0.9963555,0.0001353887,0.001859074,0.000468964,0.0007302577,0.0004508073],"domain_scores_gemma":[0.9962527,0.0004343244,0.001844005,0.0006291774,0.0005070528,0.0003327062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003546105,0.002360014,0.0008526338,0.0002833814,0.0008825124,0.00002199841,0.00003326758,0.0002382458,0.9896697,0.0001176906,0.0004451124,0.001549311],"study_design_scores_gemma":[0.0045956,0.0004638042,0.0002413765,0.0004863642,0.0004161707,0.00003217539,0.00004116278,0.00009044998,0.9899263,0.000368299,0.002933182,0.000405138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971165,0.0009733957,0.00005548163,0.0002937488,0.0004883914,0.0001288772,0.00008371996,0.00002009219,0.000839766],"genre_scores_gemma":[0.9961979,0.0004314548,0.0005154497,0.00003250108,0.00258989,0.00001593945,0.00003794784,0.00007267412,0.0001061945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00248807,"threshold_uncertainty_score":0.9997934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009022706772801621,"score_gpt":0.2831199598655521,"score_spread":0.2740972530927505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}