{"id":"W2093570598","doi":"10.1111/j.1748-1716.2011.02401.x","title":"Reverse‐mode<scp>NCX</scp>current in mouse airway smooth muscle:<scp><scp>N</scp></scp>a<sup>+</sup>and voltage dependence, contributions to<scp><scp>C</scp></scp>a<sup>2+</sup>influx and contraction, and altered expression in a model of allergen‐induced hyperresponsiveness","year":2011,"lang":"en","type":"article","venue":"Acta Physiologica","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University; St. Joseph's Hospital","funders":"","keywords":"Chemistry; Depolarization; Membrane potential; Iberiotoxin; Biophysics; Patch clamp; Voltage clamp; Electrophysiology; Charybdotoxin; Cytosol; Current clamp; Contraction (grammar); Reversal potential; Endocrinology; Internal medicine; Calcium; Receptor; Biochemistry; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001528141,0.001903773,0.002501987,0.001351986,0.001181748,0.000297599,0.001632285,0.001443241,0.00002553372],"category_scores_gemma":[0.02026539,0.001635338,0.0005134689,0.00171878,0.001062631,0.001841265,0.001535946,0.002255526,0.00007585135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003308426,"about_ca_system_score_gemma":0.00051357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004030023,"about_ca_topic_score_gemma":0.00007959202,"domain_scores_codex":[0.9882005,0.001683966,0.002293158,0.003527003,0.001423086,0.002872306],"domain_scores_gemma":[0.9851452,0.009834004,0.001368801,0.001472094,0.0007795111,0.001400382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001082088,0.001679544,0.0008430868,0.0002778172,0.00008500754,0.00006396424,0.0159663,0.01299469,0.9550653,0.0002958682,0.01197303,0.0006472223],"study_design_scores_gemma":[0.01053444,0.002392897,0.01844762,0.001399069,0.0002750726,0.0001102059,0.02689737,0.08828225,0.8071128,0.003425439,0.04042352,0.0006993779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914037,0.001133722,0.0005415892,0.0000865644,0.0008375046,0.003365327,0.001453159,0.0003481762,0.000830269],"genre_scores_gemma":[0.9902889,0.005248311,0.0003350807,0.0006680448,0.0004086215,0.0008164561,0.0001728798,0.0002043248,0.001857378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1479525,"threshold_uncertainty_score":0.9998531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04472538092270519,"score_gpt":0.2774970841750846,"score_spread":0.2327717032523794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}