{"id":"W2093605498","doi":"10.4161/19336950.2014.991255","title":"A novel disease connection for TRPM2 channels","year":2014,"lang":"en","type":"letter","venue":"Channels","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"TRPM2; Disease; Dementia; Neuroscience; Medicine; Alzheimer's disease; Amyloid (mycology); Connection (principal bundle); Internal medicine; Transient receptor potential channel; Biology; Pathology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000818617,0.0007408257,0.0008939085,0.0005035871,0.001457157,0.002136193,0.001113949,0.02133676,0.004327948],"category_scores_gemma":[0.004561948,0.0002659,0.001018941,0.0003111143,0.002266591,0.00292676,0.001011837,0.01601354,0.002781941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001518094,"about_ca_system_score_gemma":0.0008216967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005151331,"about_ca_topic_score_gemma":0.0008752716,"domain_scores_codex":[0.999374,0.0001282847,0.00005523468,0.0001432867,0.0001776276,0.0001215306],"domain_scores_gemma":[0.998363,0.001092654,0.0001141739,0.00007699138,0.0001851511,0.0001680575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0003442446,0.0001182269,0.001248469,0.0003977155,0.00006051787,0.09000006,0.0002667234,0.000236168,0.004149639,0.04895574,0.7937133,0.06050915],"study_design_scores_gemma":[0.000389629,0.0002297072,0.001324065,0.0004854994,0.00008031156,0.115084,0.0003285254,0.00166563,0.001701378,0.07701395,0.8016176,0.00007969098],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.006702152,0.03018994,0.002548556,0.8890629,0.05080208,0.0000489476,0.0001304844,0.0002247102,0.02029027],"genre_scores_gemma":[0.08012202,0.02941578,0.002383361,0.6164405,0.2523115,0.0001380507,0.0001297868,0.00006913912,0.01898996],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02133676,"threshold_uncertainty_score":0.01447845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08333122911068071,"score_gpt":0.2875748928043021,"score_spread":0.2042436636936214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}