{"id":"W2093612942","doi":"10.1159/000321109","title":"Enhancement of Mast Cell IL-6 Production by Combined Toll-Like and Nucleotide-Binding Oligomerization Domain-Like Receptor Activation","year":2010,"lang":"en","type":"article","venue":"International Archives of Allergy and Immunology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Research Nova Scotia; Canadian Institutes of Health Research; Killam Trusts","keywords":"Mast cell; Degranulation; TLR2; Receptor; Tryptase; Interleukin 5; Biology; Prostaglandin D2; Histamine; Cytokine; Immunology; Cell biology; Inflammation; Microbiology; Interleukin; TLR4; Pharmacology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000252924,0.0005501956,0.0004010666,0.0001886048,0.00008696803,0.0002864212,0.0001985144,0.0003707519,0.002171839],"category_scores_gemma":[0.0001902306,0.0001303225,0.0004668372,0.0001431146,0.0001800428,0.0002345778,0.0003577943,0.0005912641,0.0005359504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001865391,"about_ca_system_score_gemma":0.0002118377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001559957,"about_ca_topic_score_gemma":0.0003262307,"domain_scores_codex":[0.9997042,0.00006775247,0.00003288318,0.00004036273,0.00007386068,0.00008084963],"domain_scores_gemma":[0.9998856,0.0000236669,0.0000329791,0.00001337235,0.00001267836,0.00003168253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001225651,0.0001404344,0.0003390552,0.0001721591,0.00002176376,0.0001476616,0.00001148838,0.0001030085,0.9959188,0.00002046214,0.00006178506,0.001837687],"study_design_scores_gemma":[0.0003231427,0.003573591,0.006461782,0.00001995846,0.00008317913,0.0008497827,0.00002683231,0.00112587,0.9854321,0.0000377524,0.002057391,0.000008594725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929259,0.003455574,0.001925321,0.00009561503,0.0000619966,0.00009965162,0.0002806792,0.00006675068,0.001088541],"genre_scores_gemma":[0.9936074,0.001139646,0.003338932,0.00007890422,0.0000385179,0.0001088041,0.0004430837,0.00000821471,0.00123644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002171839,"threshold_uncertainty_score":0.007265568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003622821055451094,"score_gpt":0.1899222223869971,"score_spread":0.186299401331546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}