{"id":"W2093612942","doi":"10.1159/000321109","title":"Enhancement of Mast Cell IL-6 Production by Combined Toll-Like and Nucleotide-Binding Oligomerization Domain-Like Receptor Activation","year":2010,"lang":"en","type":"article","venue":"International Archives of Allergy and Immunology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Research Nova Scotia; Canadian Institutes of Health Research; Killam Trusts","keywords":"Mast cell; Degranulation; TLR2; Receptor; Tryptase; Interleukin 5; Biology; Prostaglandin D2; Histamine; Cytokine; Immunology; Cell biology; Inflammation; Microbiology; Interleukin; TLR4; Pharmacology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007285181,0.000132756,0.0002067189,0.0001770196,0.00009856158,0.000006653303,0.0001436328,0.0001110903,0.0005093865],"category_scores_gemma":[0.00002251699,0.0001301985,0.00003593761,0.00004406169,0.0004984774,0.0001013502,0.0001103803,0.000196626,0.000009287169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007466463,"about_ca_system_score_gemma":0.00001814165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008559899,"about_ca_topic_score_gemma":0.00002728035,"domain_scores_codex":[0.9991599,0.00005991138,0.0003394813,0.0002545395,0.00004137679,0.0001447981],"domain_scores_gemma":[0.9994242,0.00008253441,0.0002927386,0.0001284292,0.00005818458,0.00001393627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006760894,0.0002517296,0.0003110602,0.0000214238,0.0003010218,1.302557e-7,0.0007972423,0.000001504866,0.986374,0.003433843,0.0003403313,0.007491623],"study_design_scores_gemma":[0.001361159,0.0003904432,0.004047932,0.00003522103,0.000008146088,0.000009603208,0.0002857605,0.0000148254,0.8844189,0.0005439543,0.1087545,0.0001295864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936199,0.0002447609,0.0009718054,0.0005793361,0.001599603,0.0001443223,0.00004497176,0.00001291416,0.002782453],"genre_scores_gemma":[0.9925163,0.001178505,0.0008422459,0.00002759019,0.00002548524,0.00001296541,0.0005788398,0.00001078947,0.004807221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1084142,"threshold_uncertainty_score":0.5577425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003622821055451094,"score_gpt":0.1899222223869971,"score_spread":0.186299401331546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}