{"id":"W2093648701","doi":"10.1016/j.biomaterials.2006.10.036","title":"Long circulating lipid nanocapsules for drug detoxification","year":2006,"lang":"en","type":"article","venue":"Biomaterials","topic":"Poisoning and overdose treatments","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Université du Québec","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Docetaxel; Pharmacology; Nanocapsules; Paclitaxel; In vivo; Chemistry; Drug; Pharmacokinetics; Drug carrier; In vitro; Lipoprotein; Ethylene glycol; Biochemistry; Cholesterol; Materials science; Medicine; Nanoparticle; Organic chemistry; Internal medicine; Biology; Chemotherapy; Nanotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000298266,0.0002280344,0.0001853871,0.0001917135,0.0001734229,0.0002760955,0.0001137241,0.0003780091,0.001757556],"category_scores_gemma":[0.0002001022,0.0001254856,0.0001535293,0.00008282192,0.0002054096,0.000410948,0.0003051935,0.0004123792,0.000442617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002674127,"about_ca_system_score_gemma":0.0002214174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001534163,"about_ca_topic_score_gemma":0.0004660264,"domain_scores_codex":[0.9999442,0.00001681446,0.000003608651,0.00000818228,0.00001525735,0.00001195124],"domain_scores_gemma":[0.9999188,0.00003021735,0.00001631754,0.00000805026,0.00001345298,0.00001310823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001752313,0.00005090249,0.0001000079,0.0001250705,0.000009084581,0.000110737,0.00004187936,0.0002735692,0.9783665,0.0009185183,0.0002497238,0.01957879],"study_design_scores_gemma":[0.00003468809,0.0004839374,0.0004058809,0.00001709134,0.00003165255,0.0003005626,0.0000280834,0.0008603387,0.9892563,0.0002476096,0.008327306,0.000006702555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9225344,0.03222325,0.0364876,0.001081421,0.0003346841,0.0001153403,0.0000873447,0.0002264353,0.006909548],"genre_scores_gemma":[0.9601088,0.008008604,0.01924184,0.0002962067,0.00006032297,0.0000713401,0.00006381312,0.00003841044,0.01211068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001757556,"threshold_uncertainty_score":0.005879641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01861790511211822,"score_gpt":0.283536433619502,"score_spread":0.2649185285073838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}