{"id":"W2093648701","doi":"10.1016/j.biomaterials.2006.10.036","title":"Long circulating lipid nanocapsules for drug detoxification","year":2006,"lang":"en","type":"article","venue":"Biomaterials","topic":"Poisoning and overdose treatments","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Université du Québec","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Docetaxel; Pharmacology; Nanocapsules; Paclitaxel; In vivo; Chemistry; Drug; Pharmacokinetics; Drug carrier; In vitro; Lipoprotein; Ethylene glycol; Biochemistry; Cholesterol; Materials science; Medicine; Nanoparticle; Organic chemistry; Internal medicine; Biology; Chemotherapy; Nanotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001454645,0.0001000411,0.0001853877,0.00004679275,0.00008669403,0.00003657683,0.00003326019,0.00005146303,0.00003407776],"category_scores_gemma":[0.00004756018,0.00008171758,0.00005741038,0.00005117213,0.00001872414,0.00004666675,0.000008632327,0.000003238589,0.00003717068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006555068,"about_ca_system_score_gemma":0.00002854244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001324476,"about_ca_topic_score_gemma":0.00000676488,"domain_scores_codex":[0.9993137,0.00002053137,0.0002325495,0.0001725754,0.00008819684,0.0001724488],"domain_scores_gemma":[0.9996378,0.0000308801,0.00009448511,0.0001595965,0.00004041046,0.00003685338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005810291,0.00007443758,0.009482528,0.00008275795,0.00002516071,0.000005736998,0.00004160312,0.000001022335,0.987247,0.0001841871,0.001146561,0.001650914],"study_design_scores_gemma":[0.001158211,0.00004080293,0.132575,0.0001039846,0.00007284568,0.00002770251,0.00001419889,0.00004249938,0.8638662,0.0001517984,0.001856593,0.00009024185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979298,0.0001437554,0.0003407416,0.0001997378,0.0004031304,0.0003998093,0.00002911058,0.0001376409,0.000416235],"genre_scores_gemma":[0.9952824,0.000003661852,0.002832885,0.00004451843,0.0005597405,0.00006287901,0.0002632606,0.00002092968,0.0009297049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1233808,"threshold_uncertainty_score":0.3332346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01861790511211822,"score_gpt":0.283536433619502,"score_spread":0.2649185285073838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}