{"id":"W2093656346","doi":"10.1038/hdy.2009.121","title":"MHC genetic structure and divergence across populations of Chinook salmon (Oncorhynchus tshawytscha)","year":2009,"lang":"en","type":"article","venue":"Heredity","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Windsor; Western University","funders":"Fisheries and Oceans Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Major histocompatibility complex; Local adaptation; Balancing selection; MHC class I; Oncorhynchus; Nonsynonymous substitution; Population; Genetics; Genetic variation; Evolutionary biology; Selection (genetic algorithm); Chinook wind; MHC class II; Gene; Demography; Genome; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005563166,0.0001722078,0.0002961289,0.00003878977,0.0002436454,0.000008243471,0.0001895061,0.0003287897,0.0005066025],"category_scores_gemma":[0.00002688633,0.0001508546,0.00006099415,0.0001047718,0.000279484,0.00006828925,0.00009098233,0.0002902979,0.00005041126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001512856,"about_ca_system_score_gemma":0.00002448135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001964293,"about_ca_topic_score_gemma":0.0001553493,"domain_scores_codex":[0.99897,0.00009909581,0.0002764972,0.0002880131,0.00003441181,0.0003320234],"domain_scores_gemma":[0.9994448,0.00003431751,0.0001368839,0.0003028607,0.00005525475,0.00002586677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005375891,0.00008320846,0.04574753,0.00001121534,0.00003469473,0.000004634216,0.0005425164,0.00001140941,0.9457996,0.0002285743,0.00105083,0.006432033],"study_design_scores_gemma":[0.0007647161,0.0002850607,0.7657282,0.00001459131,0.00003484973,0.0001278128,0.0001176305,0.000007612909,0.2275809,0.002175042,0.002971942,0.0001916302],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934267,0.004872284,0.00006170644,0.00011268,0.0008600465,0.0001428905,0.000164924,0.00005295619,0.000305767],"genre_scores_gemma":[0.9986967,0.0001285607,0.0002362957,0.00007649849,0.00006935052,0.000002031012,0.0000823707,0.000006414979,0.0007017949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7199807,"threshold_uncertainty_score":0.6151672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645460815008362,"score_gpt":0.2572928388534987,"score_spread":0.2408382307034151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}