{"id":"W2093656346","doi":"10.1038/hdy.2009.121","title":"MHC genetic structure and divergence across populations of Chinook salmon (Oncorhynchus tshawytscha)","year":2009,"lang":"en","type":"article","venue":"Heredity","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Windsor; Western University","funders":"Fisheries and Oceans Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Major histocompatibility complex; Local adaptation; Balancing selection; MHC class I; Oncorhynchus; Nonsynonymous substitution; Population; Genetics; Genetic variation; Evolutionary biology; Selection (genetic algorithm); Chinook wind; MHC class II; Gene; Demography; Genome; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003567152,0.0002306857,0.0003272356,0.001298014,0.0006262837,0.0004241647,0.0004252963,0.0003413809,0.001020873],"category_scores_gemma":[0.000620942,0.0002484167,0.0002861122,0.0007600547,0.001107317,0.0002999933,0.0008284544,0.0003433344,0.0001795252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008743773,"about_ca_system_score_gemma":0.0004614097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0225431,"about_ca_topic_score_gemma":0.06469692,"domain_scores_codex":[0.9996446,0.00006204803,0.00002505695,0.0001418131,0.00004690697,0.00007953111],"domain_scores_gemma":[0.9993735,0.0001107214,0.0001706209,0.00004081216,0.000110008,0.0001944545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001552182,0.0001561622,0.8442295,0.00003574242,0.0004428867,0.0001972113,0.003887876,0.0002199354,0.1436343,0.0002355897,0.0001118757,0.005296651],"study_design_scores_gemma":[0.00001239301,0.00007178893,0.9988469,0.000001946899,0.00003030981,0.00005468052,0.000508404,0.0001328267,0.0002597387,0.00002923699,0.00004723967,0.000004498796],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9999021,0.000007608496,0.00002056766,0.000002503334,4.507758e-7,7.081493e-7,0.00002055638,6.923536e-7,0.00004467098],"genre_scores_gemma":[0.9997116,0.000008159044,0.00003979035,0.000009823082,0.000001111751,0.000003644513,0.000100644,0.000002555144,0.0001226968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0225431,"threshold_uncertainty_score":0.04482377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645460815008362,"score_gpt":0.2572928388534987,"score_spread":0.2408382307034151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}