{"id":"W2093700483","doi":"10.1111/j.1399-0039.2012.01857.x","title":"Assessment of fidelity and utility of the whole‐genome amplification for the clinical tests offered in a histocompatibility and immunogenetics laboratory","year":2012,"lang":"en","type":"article","venue":"Tissue Antigens","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"Genotyping; Human leukocyte antigen; Biology; Multiple displacement amplification; Genetics; Genome; Transplantation; Gene duplication; Immunogenetics; DNA; Human genome; Typing; Histocompatibility; Computational biology; Gene; Polymerase chain reaction; Genotype; Antigen; DNA extraction; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004397895,0.0004808946,0.0003164282,0.0006370079,0.0002289241,0.0007618106,0.0004613573,0.0008287011,0.001099311],"category_scores_gemma":[0.007813604,0.0003275884,0.0003681991,0.000304955,0.0006898972,0.0005376839,0.0004904411,0.0005811033,0.0006878784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002554033,"about_ca_system_score_gemma":0.000418228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005220476,"about_ca_topic_score_gemma":0.0005082805,"domain_scores_codex":[0.995644,0.001735746,0.0003281915,0.0009618196,0.001145489,0.00018479],"domain_scores_gemma":[0.9937711,0.003048583,0.001003715,0.0009563188,0.001088207,0.0001319246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001610735,0.00006122266,0.0123915,0.0001371128,0.00004679452,0.0000755604,0.0002294772,0.0006916571,0.9663531,0.0004025432,0.00004311497,0.01940693],"study_design_scores_gemma":[0.00001103831,0.0007168828,0.01503079,0.0000346753,0.0001300523,0.0005870293,0.0001057372,0.004915445,0.974911,0.0002446299,0.003288933,0.00002371561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7226179,0.002491659,0.2705696,0.0002166404,0.00006062895,0.000415569,0.0003716706,0.0003047808,0.002951534],"genre_scores_gemma":[0.8906847,0.0007590511,0.1063405,0.0001006736,0.00001991245,0.0001596607,0.000604143,0.0000768794,0.001254444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004397895,"threshold_uncertainty_score":0.02325857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07254717743986719,"score_gpt":0.3966849291311133,"score_spread":0.3241377516912461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}