{"id":"W2093730092","doi":"10.1038/35080103","title":"XIAP, the guardian angel","year":2001,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":252,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"National Institutes of Health","keywords":"XIAP; Caspase; Regulator; Cell biology; Apoptosis; Guardian; Inhibitor of apoptosis; Programmed cell death; Cell survival; Biology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0007816179,0.0008459355,0.001776623,0.0001288105,0.0001645379,0.00004212491,0.0009488361,0.003131145,0.0000920884],"category_scores_gemma":[0.000118122,0.0004860644,0.001781233,0.0004649308,0.0001439628,0.000002400406,0.0003306384,0.001215604,0.0002020549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004394238,"about_ca_system_score_gemma":0.0001870621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005057508,"about_ca_topic_score_gemma":0.000005378289,"domain_scores_codex":[0.9962112,0.001080371,0.000864714,0.001097424,0.0001502025,0.0005960852],"domain_scores_gemma":[0.9974436,0.0000359294,0.000691918,0.001602281,0.0000868581,0.0001394392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003707374,0.00003159828,3.186537e-7,0.002033133,0.000112818,0.00001293692,0.000002498272,6.588845e-7,0.004148346,0.0004054993,0.005043535,0.988205],"study_design_scores_gemma":[0.0001387712,0.000130676,1.374009e-7,0.0008305185,0.0006798164,0.0001003128,0.00000208607,0.00000145242,0.0006527164,0.0000996576,0.9967964,0.0005674648],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000004474061,0.9872763,0.001107382,0.00005369426,0.0009052108,0.002021546,0.00004647726,0.00002114037,0.008563818],"genre_scores_gemma":[0.00002298083,0.9925233,0.0005278492,0.0007867054,0.0009374196,0.000273671,0.002608025,0.0001166462,0.002203366],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9917529,"threshold_uncertainty_score":0.9997591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0175791515859699,"score_gpt":0.3180113164417928,"score_spread":0.3004321648558229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}