{"id":"W2093777439","doi":"10.2174/18715273113126660197","title":"Subcellular Injuries in Alzheimer’s Disease","year":2014,"lang":"en","type":"review","venue":"CNS & Neurological Disorders - Drug Targets","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital","funders":"","keywords":"Neurodegeneration; Endosome; Golgi apparatus; Endoplasmic reticulum; Cell biology; Biology; Programmed cell death; Mitochondrion; Neuroscience; Neuroinflammation; Alzheimer's disease; Subcellular localization; Microglia; Intracellular; Pathology; Disease; Medicine; Inflammation; Immunology; Apoptosis; Biochemistry; Cytoplasm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003062124,0.0009936137,0.001179451,0.002952975,0.0003949111,0.0008863764,0.0006015016,0.001062434,0.003185126],"category_scores_gemma":[0.0003849824,0.0002377445,0.0004184661,0.002844259,0.0004659507,0.001276779,0.0007344962,0.001248631,0.002686577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005432109,"about_ca_system_score_gemma":0.001067801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00121255,"about_ca_topic_score_gemma":0.002039393,"domain_scores_codex":[0.9998422,0.00002160389,0.00002604356,0.00002492314,0.00006943757,0.00001565765],"domain_scores_gemma":[0.9998721,0.00003681095,0.0000262698,0.000004488398,0.0000449073,0.00001544825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005926219,0.00008077678,0.0002375457,0.02421181,0.00007092275,0.0003977618,0.0001321075,0.000293032,0.002394012,0.003407282,0.03041668,0.9382988],"study_design_scores_gemma":[0.00001516912,0.0001055794,0.001341738,0.004613091,0.00009305761,0.003273943,0.0001199476,0.0000561339,0.0004805044,0.003058928,0.9868236,0.00001816649],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001143892,0.9984881,0.00006680574,0.0001063384,0.0001346994,0.000004961194,0.00001119721,0.000007369949,0.001066133],"genre_scores_gemma":[0.0007010489,0.9984438,0.0001079958,0.00007987853,0.00008101883,0.000004184106,0.00001760372,8.146657e-7,0.0005637222],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003185126,"threshold_uncertainty_score":0.01065528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04214750574567525,"score_gpt":0.3403541258693908,"score_spread":0.2982066201237156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}