{"id":"W2093813815","doi":"10.1016/s1359-6101(00)00034-4","title":"X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis","year":2001,"lang":"en","type":"review","venue":"Cytokine & Growth Factor Reviews","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":155,"is_retracted":false,"has_abstract":false,"ca_institutions":"Amgen (Canada); Ontario Institute for Cancer Research; University of Toronto","funders":"Amgen","keywords":"HBx; Signal transduction; Biology; Protein kinase R; Signal transducing adaptor protein; Protein kinase A; Janus kinase; Protein kinase B; ASK1; Cancer research; Hepatitis B virus; Kinase; Cell biology; Protein kinase C; Mitogen-activated protein kinase kinase; Virology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004748466,0.0006715011,0.001187423,0.001015043,0.0002060108,0.0007467264,0.0007169467,0.0007165048,0.001493743],"category_scores_gemma":[0.0003629124,0.0001978798,0.0002541675,0.001360603,0.0003936971,0.0009109497,0.0004062006,0.0006002131,0.001131566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003851424,"about_ca_system_score_gemma":0.0006482954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006966724,"about_ca_topic_score_gemma":0.0009662212,"domain_scores_codex":[0.9998679,0.00002741378,0.00002071439,0.00002710508,0.00004421169,0.00001259978],"domain_scores_gemma":[0.9998363,0.00007536959,0.00003252642,0.000006733788,0.00003429112,0.00001473504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005233226,0.00007215741,0.0007900586,0.01148059,0.00008255935,0.0006746997,0.0001081125,0.0002924235,0.03375211,0.001784014,0.005445434,0.9449946],"study_design_scores_gemma":[0.0001554108,0.0008849099,0.009477076,0.003634489,0.0004514982,0.006105352,0.0003980178,0.0002301848,0.0198717,0.002868727,0.9558634,0.00005934495],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000939798,0.9980919,0.0001960056,0.00007372033,0.00009168827,0.000004121416,0.00001077849,0.000005787978,0.0005861857],"genre_scores_gemma":[0.001916549,0.9972434,0.0001766106,0.00004767803,0.00008327138,0.00000580932,0.00002053329,8.252547e-7,0.0005052995],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001493743,"threshold_uncertainty_score":0.004997075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04573101984530762,"score_gpt":0.2908932350543971,"score_spread":0.2451622152090895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}