{"id":"W2093870910","doi":"10.1038/sj.onc.1207937","title":"The origin of hematopoietic cell type diversity","year":2004,"lang":"en","type":"review","venue":"Oncogene","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Cancer Institute; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Biology; Transcription factor; Cell biology; Lymphopoiesis; Cell fate determination; Stem cell; Haematopoiesis; Wnt signaling pathway; Cellular differentiation; Embryonic stem cell; Progenitor cell; Gene regulatory network; Signal transduction; Genetics; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002412901,0.0001597894,0.0003511743,0.00002966816,0.0001709838,0.00001098315,0.000714345,0.0002480161,0.00003168402],"category_scores_gemma":[0.0001224416,0.0001050744,0.000232926,0.0002508329,0.0002309282,6.736727e-7,0.0007507222,0.0001512819,0.0001159251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005041449,"about_ca_system_score_gemma":0.0007998663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002062685,"about_ca_topic_score_gemma":0.00001054514,"domain_scores_codex":[0.9989306,0.00006707371,0.0002440871,0.0002709128,0.0002577561,0.0002295128],"domain_scores_gemma":[0.9989356,0.00005180227,0.0001586467,0.0006246197,0.0001028063,0.00012651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002363912,0.0002765123,0.000007531891,0.009732402,0.0003262981,0.000009889667,0.00001606389,6.171446e-7,0.004664348,0.0006247086,0.01827703,0.966041],"study_design_scores_gemma":[0.00009342417,0.00009160035,4.988965e-7,0.000357508,0.00009413846,0.000006782885,0.000003651746,7.450181e-8,0.001851983,0.00008976014,0.9973063,0.0001042598],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005488445,0.9974902,0.00009534932,0.00003690782,0.00007618399,0.0003655732,0.00005738784,0.000005244556,0.001818313],"genre_scores_gemma":[0.0002234437,0.9975115,0.0001662116,0.00001297456,0.0001173801,0.00003271413,0.0002267664,0.0000215779,0.00168743],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9790293,"threshold_uncertainty_score":0.4284809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03996349032343389,"score_gpt":0.3516681627866431,"score_spread":0.3117046724632093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}