{"id":"W2093877605","doi":"10.1128/jvi.74.4.2052-2056.2000","title":"Herpes Simplex Virus ICP0 Mutants Are Hypersensitive to Interferon","year":2000,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":222,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Biology; Herpes simplex virus; Transactivation; Viral replication; Interferon; Virology; Virus; Gene; Molecular biology; Mutant; Transcription (linguistics); Gene product; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001276944,0.0005454248,0.0002403265,0.0002496932,0.0001989375,0.0002836458,0.0002769663,0.0002876614,0.001941889],"category_scores_gemma":[0.0001807149,0.0001904996,0.0003027453,0.000159997,0.0003125955,0.0001680232,0.0002607459,0.000523897,0.0007321307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002674673,"about_ca_system_score_gemma":0.0001336306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003978253,"about_ca_topic_score_gemma":0.0002730089,"domain_scores_codex":[0.9998535,0.00002044537,0.00001872441,0.00002570815,0.00005158203,0.00002995349],"domain_scores_gemma":[0.999797,0.0000363241,0.00006411105,0.00003227899,0.00001613835,0.00005415879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008665097,0.00001885426,0.0001715044,0.0000148687,0.000005028643,0.00009413706,0.00001260243,0.00004101772,0.9985982,0.0001129901,0.00006454028,0.0007796028],"study_design_scores_gemma":[0.0000155223,0.000231951,0.003503504,0.000005144042,0.00001239251,0.001147824,0.00002440746,0.0004953839,0.9917128,0.0001211541,0.002722131,0.000007787082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934641,0.0005603895,0.003013662,0.0000596032,0.0000677943,0.00004128077,0.0005069036,0.0002473553,0.002039059],"genre_scores_gemma":[0.9921547,0.0003908646,0.002999253,0.00005000317,0.00001460883,0.0000615016,0.000885537,0.0001085848,0.003334836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001941889,"threshold_uncertainty_score":0.006496251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01556479220407251,"score_gpt":0.3008714438849264,"score_spread":0.2853066516808539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}