{"id":"W2093900959","doi":"10.1055/s-2005-916165","title":"A Step Change in Oral Anticoagulation: Lack of Coagulation Monitoring with Ximelagatran","year":2005,"lang":"en","type":"review","venue":"Seminars in Vascular Medicine","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; Hamilton General Hospital","funders":"","keywords":"Ximelagatran; Medicine; Partial thromboplastin time; Prothrombin time; Coagulation; Anticoagulant; Direct thrombin inhibitor; Coagulation testing; Thromboplastin; Therapeutic index; Pharmacology; Bioequivalence; Thrombin time; Clotting time; Internal medicine; Warfarin; Pharmacokinetics; Atrial fibrillation; Drug; Dabigatran","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005037021,0.0004367222,0.0006707864,0.0005143662,0.000356571,0.001613468,0.0009499382,0.001596303,0.001103874],"category_scores_gemma":[0.01209419,0.0001765279,0.0002953511,0.0004970093,0.001006786,0.001535699,0.0005493729,0.002194456,0.0007711374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009546261,"about_ca_system_score_gemma":0.001431602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008285409,"about_ca_topic_score_gemma":0.0008392452,"domain_scores_codex":[0.9959741,0.0009199801,0.0006733575,0.0005401184,0.001794562,0.00009786335],"domain_scores_gemma":[0.9945667,0.002127717,0.0007609272,0.0004671317,0.001663987,0.0004135677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008602481,0.0003772484,0.06668463,0.001257845,0.0001345107,0.004432587,0.00055074,0.0003976258,0.02632211,0.004951635,0.02191508,0.8721156],"study_design_scores_gemma":[0.0003715919,0.007300378,0.2260515,0.004376528,0.0007789413,0.1038551,0.002114329,0.01020574,0.1363555,0.0197684,0.4884703,0.0003516716],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5620123,0.1148136,0.09400729,0.1662018,0.008517941,0.0006964048,0.0006633693,0.005115418,0.04797194],"genre_scores_gemma":[0.8476596,0.02468948,0.07008737,0.04869844,0.001815649,0.0001659531,0.0003747068,0.0002080867,0.006300608],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.005037021,"threshold_uncertainty_score":0.02663863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2118378094020203,"score_gpt":0.4347809898419719,"score_spread":0.2229431804399516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}