{"id":"W2093904931","doi":"10.1002/cbic.200700027","title":"Correctors of Protein Trafficking Defects Identified by a Novel High‐Throughput Screening Assay","year":2007,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institutes of Health","keywords":"High-throughput screening; Mutant; Small molecule; Computational biology; Biology; Chemistry; Gene; Bioinformatics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008998021,0.0002203682,0.0004343782,0.0001434175,0.00006964338,0.000024741,0.0001834327,0.0001436775,0.00008806001],"category_scores_gemma":[0.001525613,0.0002095607,0.0001420181,0.0005166277,0.0002038804,0.0001092779,0.00009124546,0.0003165123,0.00001557061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001214972,"about_ca_system_score_gemma":0.00009346082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001027165,"about_ca_topic_score_gemma":0.00001665691,"domain_scores_codex":[0.9978006,0.00001988096,0.0004488172,0.000432764,0.0007233229,0.0005745997],"domain_scores_gemma":[0.9986655,0.0002853916,0.000186106,0.000392494,0.0002178893,0.0002526498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003487583,0.0002536777,0.00105976,0.0003311467,0.00006612327,0.00002206332,0.0001522857,0.000003281041,0.9884972,0.00005978308,0.001443123,0.00776277],"study_design_scores_gemma":[0.001938705,0.0002003163,0.004339947,0.0005855407,0.00003934264,0.0000314637,0.0002488992,0.0001146914,0.9906533,0.00001462316,0.001646277,0.0001869167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9542812,0.0009127942,0.04271618,0.00009100528,0.0001219354,0.0006723335,0.00001827312,0.0001094953,0.001076855],"genre_scores_gemma":[0.981918,0.000005469798,0.01640986,0.0000462956,0.0001344522,0.00002389989,0.00008801917,0.00004755525,0.001326476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02763685,"threshold_uncertainty_score":0.8545639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01948506090483575,"score_gpt":0.3018618925571513,"score_spread":0.2823768316523156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}