{"id":"W2093922965","doi":"10.1016/j.antiviral.2009.08.009","title":"Human H1 promoter expressed short hairpin RNAs (shRNAs) suppress avian influenza virus replication in chicken CH-SAH and canine MDCK cells","year":2009,"lang":"en","type":"article","venue":"Antiviral Research","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Krell Institute; Ontario Ministry of Agriculture, Food and Rural Affairs; Poultry Industry Council; Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Poultry Research Council","keywords":"Virology; Biology; Viral replication; Replication (statistics); Small hairpin RNA; Influenza A virus; Avian influenza virus; Virus; Cell biology; Gene; Influenza A virus subtype H5N1; RNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000324047,0.0002682774,0.0002783665,0.0002771663,0.0002556145,0.0003590877,0.0002146842,0.0002590019,0.001196497],"category_scores_gemma":[0.0001916249,0.0002180852,0.0002657333,0.0001476893,0.0003647071,0.0002125648,0.0001823054,0.0006761894,0.0003619634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004931013,"about_ca_system_score_gemma":0.0002576952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00238124,"about_ca_topic_score_gemma":0.004362179,"domain_scores_codex":[0.9997483,0.00005025016,0.00003362635,0.00004892759,0.00005023086,0.00006875422],"domain_scores_gemma":[0.9997072,0.0001320819,0.0000399695,0.00005119676,0.00002790539,0.00004173401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001739601,0.00002393729,0.0001987402,0.00001910452,0.000003778626,0.00001805882,0.00002907632,0.00005550034,0.9988474,0.000122431,0.00006417274,0.0004438076],"study_design_scores_gemma":[0.00002222361,0.000320437,0.002819202,0.000003476123,0.00001084898,0.00007629776,0.00006393559,0.001287233,0.9941127,0.00002304288,0.001257727,0.000002820823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996747,0.0005814491,0.001055442,0.00007449798,0.00004323059,0.00003241767,0.0004108776,0.00004042116,0.00101456],"genre_scores_gemma":[0.9938373,0.0003006273,0.001950652,0.00004206707,0.00001355365,0.00004078684,0.0008488029,0.00001870173,0.002947589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00238124,"threshold_uncertainty_score":0.004734814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06178441009399893,"score_gpt":0.3820911159581269,"score_spread":0.320306705864128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}