{"id":"W2093944201","doi":"10.1053/j.seminoncol.2013.05.011","title":"Selected Toxicities of Targeted Therapies: Presentation and Management","year":2013,"lang":"en","type":"article","venue":"Seminars in Oncology","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Targeted therapy; Intensive care medicine; Dosing; Toxicity; Renal cell carcinoma; Disease; Radiation therapy; Intervention (counseling); Oncology; Cancer; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007443686,0.00008099146,0.0002246966,0.0001475013,0.00001256356,0.000003010338,0.00003284735,0.0000701648,0.000202507],"category_scores_gemma":[0.00002047139,0.00006679927,0.00001839166,0.000171096,0.00008967054,0.00003801305,0.00002911957,0.00006352235,0.000008931899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001443486,"about_ca_system_score_gemma":0.00003037726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001394289,"about_ca_topic_score_gemma":0.00002604663,"domain_scores_codex":[0.9993666,0.00006238261,0.0001952747,0.0001393683,0.00009718056,0.0001392342],"domain_scores_gemma":[0.9996271,0.00009720542,0.000061135,0.0001121267,0.00006389916,0.00003852531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009176597,0.001386094,0.4182305,0.0008161726,0.0006157433,0.000481754,0.01607265,0.00002114474,0.2377288,0.001046688,0.01571097,0.3069718],"study_design_scores_gemma":[0.002756892,0.002483425,0.9393631,0.000152247,0.00006875928,0.00008273503,0.004864736,0.00020744,0.04639383,0.0008139606,0.002708821,0.0001041145],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849231,0.002500972,0.00001134576,0.0006781394,0.00004689062,0.0007197476,9.818633e-7,0.00001560252,0.01110318],"genre_scores_gemma":[0.9918329,0.002099018,0.004355419,0.0001182492,0.00001601074,0.0001425077,0.00001754812,0.000009068557,0.001409317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5211325,"threshold_uncertainty_score":0.2723995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01427330744296644,"score_gpt":0.2872275127491344,"score_spread":0.2729542053061679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}