{"id":"W2093970951","doi":"10.1002/jor.21536","title":"Mechanically induced calcium signaling in chondrocytes in situ","year":2011,"lang":"en","type":"article","venue":"Journal of Orthopaedic Research®","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research","keywords":"Mechanotransduction; Calcium; Calcium signaling; Cell biology; Extracellular matrix; Chemistry; Calcium in biology; Signal transduction; Extracellular; In situ; Cartilage; Cell signaling; Biophysics; Anatomy; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003269102,0.000144528,0.0004911553,0.001268339,0.00004253509,0.00001857047,0.0001913433,0.0001710968,0.0002748595],"category_scores_gemma":[0.0007770363,0.0001132219,0.0001846558,0.0007247929,0.00005636448,0.0002369779,0.00007250631,0.00127342,0.00003434544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002264351,"about_ca_system_score_gemma":0.000539621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006835912,"about_ca_topic_score_gemma":0.000210473,"domain_scores_codex":[0.9971206,0.0002827779,0.0007937845,0.000201044,0.001047057,0.000554756],"domain_scores_gemma":[0.9987077,0.0001786866,0.0001700543,0.0002023682,0.0003822526,0.0003589632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002317766,0.001011339,0.03914262,0.00006519516,0.00004480658,0.01232014,0.001791664,4.927298e-7,0.9044941,0.0007523458,0.00008650302,0.03797305],"study_design_scores_gemma":[0.02446433,0.01912285,0.04987318,0.003113887,0.00007887415,0.001504934,0.003056364,0.00001627087,0.8909326,0.006824222,0.0006712903,0.0003412563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935001,0.000778086,0.00003291944,0.0003178199,0.0002146332,0.0003549382,6.747428e-7,0.000009197905,0.004791682],"genre_scores_gemma":[0.9973317,0.0001744726,0.00190642,0.00007996475,0.0002198125,0.00001204657,0.000001621882,0.00002559773,0.0002483592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03763179,"threshold_uncertainty_score":0.5532445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1657597306057361,"score_gpt":0.3761413885343173,"score_spread":0.2103816579285812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}