{"id":"W2093982372","doi":"10.1016/j.healun.2004.11.150","title":"α-gal induces monocyte β-2 integrin activation and firm adhesion on ICAM-1 and ICAM-2","year":2005,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Integrin; Monocyte; ICAM-1; Adhesion; Cell biology; Cell adhesion; Endothelium; Endothelial stem cell; Infiltration (HVAC); Cell adhesion molecule; Chemistry; Immunology; Cell; Cancer research; Medicine; Biology; In vitro; Biochemistry; Internal medicine; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001802386,0.0005283019,0.0002591973,0.0003325329,0.0002120849,0.0005848581,0.0002178872,0.000368959,0.002525404],"category_scores_gemma":[0.0001835524,0.0002765073,0.0005492527,0.0002100789,0.0002354975,0.000233306,0.000339215,0.001389541,0.0006261608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002851349,"about_ca_system_score_gemma":0.0001551271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004790291,"about_ca_topic_score_gemma":0.0006189242,"domain_scores_codex":[0.9996252,0.00008726662,0.00002034717,0.00002360221,0.00004637304,0.0001971577],"domain_scores_gemma":[0.9998679,0.00003959827,0.0000185408,0.0000238589,0.00001119135,0.00003884737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008157835,0.0002120399,0.0002832571,0.00003262912,0.00001192209,0.0001185677,0.00003299589,0.00005693582,0.9967747,0.000209039,0.0001012856,0.001350893],"study_design_scores_gemma":[0.0001491717,0.001080864,0.01361014,0.00001605371,0.00003681862,0.0003950866,0.0001783334,0.001037944,0.9816924,0.0002408007,0.001555053,0.000007199766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963824,0.000537003,0.0009224503,0.0001414591,0.00005364907,0.00001799521,0.0001142393,0.000030105,0.001800645],"genre_scores_gemma":[0.9962656,0.0003644636,0.0005272041,0.0001796621,0.00003518131,0.00002777701,0.0003812395,0.00001005896,0.002208882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002525404,"threshold_uncertainty_score":0.008448362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0177998583553843,"score_gpt":0.2912203597664053,"score_spread":0.273420501411021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}