{"id":"W2093995758","doi":"10.1371/journal.pone.0104234","title":"Mapping of a Chromosome 12 Region Associated with Airway Hyperresponsiveness in a Recombinant Congenic Mouse Strain and Selection of Potential Candidate Genes by Expression and Sequence Variation Analyses","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University Health Centre; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; American Asthma Foundation","keywords":"Congenic; Quantitative trait locus; Biology; Genetics; Candidate gene; Gene; Genetic linkage; Locus (genetics); Chromosome 7 (human); Phenotype; Chromosome; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002888895,0.0005447288,0.0003924256,0.001073254,0.0002402295,0.0002592148,0.000392946,0.000441698,0.002474701],"category_scores_gemma":[0.0003130641,0.0003498052,0.0005406674,0.0005384742,0.0002691638,0.00008131746,0.0003316683,0.0008130214,0.0006614279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002382435,"about_ca_system_score_gemma":0.000215325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00150304,"about_ca_topic_score_gemma":0.002050551,"domain_scores_codex":[0.9996172,0.00005575753,0.00003382317,0.0001314572,0.0001033729,0.00005840593],"domain_scores_gemma":[0.9994061,0.0001580387,0.0002182963,0.000042041,0.0000479888,0.0001275325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000131353,0.00003083197,0.0004562837,0.0000158418,0.000006758065,0.00008727844,0.00001113532,0.00004136825,0.9984047,0.0000316306,0.00001283295,0.0007699552],"study_design_scores_gemma":[0.0002128329,0.001614193,0.2294697,0.00005112898,0.0002393458,0.003696176,0.0001304504,0.003700463,0.7537705,0.0001498742,0.006899807,0.00006557782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869731,0.0005236862,0.009848475,0.00007801316,0.00002562129,0.0001041195,0.001490399,0.0001789845,0.0007775542],"genre_scores_gemma":[0.963949,0.0008070894,0.02308238,0.0001119281,0.0000289889,0.0001904864,0.005526351,0.000139104,0.006164632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002474701,"threshold_uncertainty_score":0.008278668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02403050581867844,"score_gpt":0.2290449274963071,"score_spread":0.2050144216776286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}