{"id":"W2094041961","doi":"10.1128/ec.05273-11","title":"Adaptation of Cryptococcus neoformans to Mammalian Hosts: Integrated Regulation of Metabolism and Virulence","year":2011,"lang":"en","type":"review","venue":"Eukaryotic Cell","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Burroughs Wellcome Fund","keywords":"Cryptococcus neoformans; Biology; Virulence; Microbiology; Cryptococcosis; Adaptation (eye); Virulence factor; Cell biology; Extracellular; Yeast; Immune system; Transcription factor; Cellular adaptation; Cryptococcus; Immunology; Gene; Genetics; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001795282,0.0002363174,0.001169662,0.0003039067,0.0000393199,0.000004892631,0.00006144358,0.0001413557,0.0001418705],"category_scores_gemma":[0.00006387044,0.0001742133,0.0001797234,0.0004166791,0.00007629967,0.0000552577,0.00005046442,0.0001680423,0.00002845638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004226297,"about_ca_system_score_gemma":0.0001106999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004080644,"about_ca_topic_score_gemma":0.00003351129,"domain_scores_codex":[0.9988308,0.00005708581,0.0006206417,0.0002188113,0.0001293617,0.0001433067],"domain_scores_gemma":[0.9990366,0.00006560171,0.0003418672,0.0002622323,0.0002120403,0.00008164917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005953674,0.0002186713,0.0004218492,0.02315019,0.0002010437,0.000003502375,0.001207122,0.00000731721,0.00004649048,0.0007018553,0.0007941799,0.9731882],"study_design_scores_gemma":[0.0006433737,0.0008236157,0.02463386,0.01313441,0.003202979,0.00003611461,0.0004085564,0.00008782803,0.0003634372,0.00006166488,0.9562246,0.00037959],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001287681,0.9922132,0.0006651065,0.0000125631,0.0002382443,0.001146022,0.00004728168,0.00002088858,0.004368966],"genre_scores_gemma":[0.00389352,0.9926857,0.001895065,0.00001269777,0.00006012715,0.00005012952,0.00006933443,0.00002613156,0.001307266],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9728087,"threshold_uncertainty_score":0.7104212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0469798637355099,"score_gpt":0.2926747390757463,"score_spread":0.2456948753402364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}