{"id":"W2094064070","doi":"10.1053/joca.2000.0368","title":"Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation","year":2001,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":294,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Genentech","keywords":"Osteoarthritis; Synovial joint; Cartilage; Extracellular matrix; Synovial membrane; Transforming growth factor; Arthritis; Synovial fluid; Knee Joint; Transforming growth factor beta; Chemistry; Hyperplasia; Pathology; Medicine; Articular cartilage; Anatomy; Immunology; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004024081,0.0004498535,0.0002936253,0.0007875065,0.0002108147,0.0005633131,0.0002211056,0.0004452757,0.001011253],"category_scores_gemma":[0.0002804392,0.000523585,0.0003208441,0.0003020563,0.0005058026,0.0004818761,0.0002451466,0.0008802925,0.0005394442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002776781,"about_ca_system_score_gemma":0.000269024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005721506,"about_ca_topic_score_gemma":0.0008795287,"domain_scores_codex":[0.9996593,0.00005828052,0.00004787464,0.00003940709,0.0001146702,0.00008048505],"domain_scores_gemma":[0.9992537,0.0001363119,0.0002687471,0.00008815219,0.0000578033,0.0001953417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001170586,0.00001160058,0.0001214898,0.000024466,0.00000280463,0.00004354283,0.000008585343,0.00001815881,0.9993058,0.00007430644,0.00000613599,0.000265907],"study_design_scores_gemma":[0.00002693833,0.0002265115,0.002536534,0.000007996941,0.00002643488,0.0003408786,0.0000374612,0.0003643325,0.9957184,0.00006351046,0.0006473679,0.000003520488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880029,0.005029035,0.004374112,0.0001372625,0.00004800148,0.0000279949,0.0004206603,0.0001095373,0.001850375],"genre_scores_gemma":[0.9920281,0.001392742,0.002881605,0.00004448312,0.00001837934,0.0000239076,0.0003901401,0.00004116367,0.003179678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001011253,"threshold_uncertainty_score":0.003382981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04220685185174463,"score_gpt":0.2861345274847188,"score_spread":0.2439276756329742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}