{"id":"W2094077145","doi":"10.1016/j.ab.2013.04.018","title":"Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of titanium oxide-enriched peptides for detection of aged organophosphorus adducts on human butyrylcholinesterase","year":2013,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Pesticide Exposure and Toxicity","field":"Agricultural and Biological Sciences","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Defence Research and Development Canada","funders":"National Cancer Institute; U.S. Public Health Service; Agence Nationale de la Recherche","keywords":"Adduct; Chemistry; Butyrylcholinesterase; Nerve agent; Mass spectrometry; Chromatography; Tandem mass spectrometry; Peptide; Desorption; Biochemistry; Organic chemistry; Enzyme; Acetylcholinesterase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001508304,0.0001628548,0.0003173354,0.00003062036,0.00007116514,0.00002005696,0.0001718434,0.0001961386,0.0004892608],"category_scores_gemma":[0.0003135666,0.00008303463,0.0001574653,0.0005367047,0.0001002864,0.00007054509,0.00002745741,0.0000972089,0.00002390166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003989583,"about_ca_system_score_gemma":0.00001287726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007794947,"about_ca_topic_score_gemma":0.00001067106,"domain_scores_codex":[0.9987808,0.00003242828,0.000480917,0.000276498,0.0002324192,0.0001969531],"domain_scores_gemma":[0.9989229,0.000258726,0.0002765932,0.0001195902,0.0003242681,0.00009786536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007176501,0.0002195163,0.001945791,0.00005775278,0.0000399555,7.10729e-7,0.000004079626,0.000003501913,0.9969739,0.00003172444,0.0001801944,0.0004711307],"study_design_scores_gemma":[0.0002214887,0.0003295212,0.07602125,0.00003015507,0.00006453905,0.000002160747,0.00003779693,0.0001329425,0.9227034,0.0003169917,0.000008144983,0.0001315526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992014,0.00003344732,0.000163578,0.00009502148,0.00002210342,0.0001909035,0.00006477773,0.00002666173,0.0002020982],"genre_scores_gemma":[0.9985073,0.000006302494,0.0005712523,0.00002825971,0.0001012378,0.00001046383,0.000166185,0.000002719039,0.0006063381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07427041,"threshold_uncertainty_score":0.5357062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01559888604020165,"score_gpt":0.2465096803399416,"score_spread":0.23091079429974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}