{"id":"W2094164510","doi":"10.1016/j.imlet.2009.04.002","title":"Induction of tolerogenic vs immunogenic dendritic cells (DCs) in the presence of GM-CSF is regulated by the strength of signaling from monophosphoryl lipid A (MPLA) in association with glutathione and fetal hemoglobin gamma-chain","year":2009,"lang":"en","type":"article","venue":"Immunology Letters","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"Prairie Research Institute","keywords":"CTL*; Glutathione; FOXP3; Immunology; Biology; In vivo; Stimulation; Cell biology; Dendritic cell; Fetal bovine serum; In vitro; Chemistry; Immune system; CD8; Biochemistry; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003806692,0.0003910439,0.000331472,0.0003120819,0.0002161993,0.0006273166,0.0001662029,0.0003540019,0.0009340344],"category_scores_gemma":[0.0004010956,0.000206488,0.0002605884,0.0002351468,0.0003312262,0.0002664248,0.0003275718,0.001087755,0.0002961911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003421049,"about_ca_system_score_gemma":0.0002572732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001877478,"about_ca_topic_score_gemma":0.0003305748,"domain_scores_codex":[0.9995728,0.00009027166,0.00004457551,0.00004496215,0.00008366458,0.0001637617],"domain_scores_gemma":[0.9992974,0.0002163312,0.0001557696,0.00006963802,0.00007853835,0.0001823059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004294971,0.00004353435,0.00049789,0.00003004762,0.00000432483,0.0000638507,0.00003348217,0.00006465192,0.9976218,0.0001539126,0.00003484408,0.001022209],"study_design_scores_gemma":[0.0001019251,0.000485247,0.00701509,0.00001200611,0.00003923873,0.0002590337,0.00008938879,0.0007344407,0.9895496,0.00018683,0.001519751,0.000007432798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974748,0.0006292128,0.0006574894,0.00008711984,0.00003535712,0.00002643269,0.0001605994,0.00002413525,0.0009047699],"genre_scores_gemma":[0.9981815,0.0003270464,0.0007037582,0.00008243879,0.00003020339,0.00002312039,0.0002085523,0.00001418392,0.0004292248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009340344,"threshold_uncertainty_score":0.003124654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004818438804678744,"score_gpt":0.1943767207074396,"score_spread":0.1895582819027609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}