{"id":"W2094164510","doi":"10.1016/j.imlet.2009.04.002","title":"Induction of tolerogenic vs immunogenic dendritic cells (DCs) in the presence of GM-CSF is regulated by the strength of signaling from monophosphoryl lipid A (MPLA) in association with glutathione and fetal hemoglobin gamma-chain","year":2009,"lang":"en","type":"article","venue":"Immunology Letters","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"Prairie Research Institute","keywords":"CTL*; Glutathione; FOXP3; Immunology; Biology; In vivo; Stimulation; Cell biology; Dendritic cell; Fetal bovine serum; In vitro; Chemistry; Immune system; CD8; Biochemistry; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008478839,0.0002628707,0.0005917478,0.0002087996,0.0001061987,0.00001187083,0.0004769103,0.0003922123,0.00005179729],"category_scores_gemma":[0.0001047016,0.0001899817,0.0001118459,0.0004796976,0.0005798425,0.0001588457,0.00004867677,0.0006472124,0.000003772842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001085637,"about_ca_system_score_gemma":0.00007158938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001666853,"about_ca_topic_score_gemma":0.00003947644,"domain_scores_codex":[0.9971061,0.001232768,0.000819587,0.0003191002,0.000114032,0.0004083524],"domain_scores_gemma":[0.9978104,0.000940618,0.0006812979,0.0004817498,0.00007918314,0.000006715356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003209313,0.000262023,0.003138393,0.00001004595,0.0004775444,0.00000370956,0.005117319,0.00005522761,0.9846092,0.00001758214,0.0001981072,0.002901501],"study_design_scores_gemma":[0.003213293,0.0006580883,0.06333324,0.0001634319,0.0000775806,0.00005076528,0.001644566,0.0000170827,0.930484,0.00005189623,0.0001328106,0.0001732342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787291,0.01859738,0.00003225888,0.001927436,0.0001837595,0.0004545712,0.00005657757,0.00001281026,0.000006072672],"genre_scores_gemma":[0.9985868,0.0007843301,0.00004688372,0.0004310802,0.000006618541,0.00002132754,0.00004879219,0.00001521676,0.00005890715],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06019484,"threshold_uncertainty_score":0.7747229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004818438804678744,"score_gpt":0.1943767207074396,"score_spread":0.1895582819027609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}