{"id":"W2094178892","doi":"10.1039/c4an01352b","title":"Structured oligonucleotides for target indexing to allow single-vessel PCR amplification and solid support microarray hybridization","year":2014,"lang":"en","type":"article","venue":"The Analyst","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Oligonucleotide; Microarray; Chemistry; Molecular biology; DNA microarray; Polymerase chain reaction; Computational biology; Biology; Gene; Biochemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000894498,0.0009680566,0.0005980381,0.000376497,0.0001338538,0.000477996,0.0007548889,0.0008239009,0.00175955],"category_scores_gemma":[0.001013567,0.0004032812,0.0005603766,0.0003546276,0.0002908849,0.0004563646,0.0002672648,0.0007120099,0.001364829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003262696,"about_ca_system_score_gemma":0.000421674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001854166,"about_ca_topic_score_gemma":0.0003561071,"domain_scores_codex":[0.99903,0.0002063817,0.00009480822,0.0002560569,0.0003184684,0.00009428598],"domain_scores_gemma":[0.9993041,0.0002519853,0.000174129,0.00008554226,0.0001257131,0.00005854369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003312234,0.00002146145,0.00003287166,0.00006732828,0.000003495326,0.00001296268,0.000008050717,0.0001657732,0.9980053,0.00007111509,0.00002344668,0.001555207],"study_design_scores_gemma":[0.000005936963,0.0002446726,0.0001920364,0.000003223988,0.00001004943,0.00005320309,0.000005280726,0.0008064158,0.9975411,0.00003115589,0.001101149,0.000005762297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6277386,0.004160994,0.361423,0.0002287894,0.0002918942,0.0009898705,0.0009187236,0.001667097,0.002581026],"genre_scores_gemma":[0.4722618,0.001840929,0.5165707,0.0003839465,0.0000694899,0.001160092,0.002592736,0.0002362272,0.004883999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00175955,"threshold_uncertainty_score":0.005886316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01432964408485297,"score_gpt":0.2615655862666209,"score_spread":0.2472359421817679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}