{"id":"W2094241860","doi":"10.1056/nejmoa1215541","title":"Dolutegravir plus Abacavir–Lamivudine for the Treatment of HIV-1 Infection","year":2013,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":878,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Dolutegravir; Abacavir; Medicine; Lamivudine; Virology; Integrase inhibitor; Regimen; Human immunodeficiency virus (HIV); Antiretroviral therapy; Virus; Internal medicine; Viral load; Hepatitis B virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003370672,0.0001856239,0.0006005288,0.0001872249,0.00006520598,0.000006628833,0.00006477439,0.00005667518,0.0003072844],"category_scores_gemma":[0.0001296303,0.00008122395,0.0001683647,0.0001593411,0.00008949399,0.00007620741,0.000005853964,0.000112404,0.00001753997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001836069,"about_ca_system_score_gemma":0.0002093689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002399114,"about_ca_topic_score_gemma":0.00004002747,"domain_scores_codex":[0.9987256,0.00003419068,0.0005956219,0.0001062377,0.0003530311,0.0001853513],"domain_scores_gemma":[0.9985293,0.0004408484,0.0003492776,0.0001698956,0.0003035252,0.0002071107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001987146,0.0006980037,0.03803532,0.00009480541,0.001688799,0.00007346356,0.006179759,0.00006433878,0.002933756,0.0002582408,0.07238622,0.8756002],"study_design_scores_gemma":[0.1698557,0.009801763,0.08845765,0.0006456648,0.00220328,0.001144846,0.0005408712,0.0004555273,0.002904985,0.0007818942,0.7230367,0.0001710691],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8732094,0.007626095,0.007280442,0.1060672,0.001456992,0.001915071,0.000007587825,0.00002752765,0.002409668],"genre_scores_gemma":[0.9668818,0.006025749,0.002202048,0.0001989313,0.004450582,0.00003447578,0.00002967448,0.00002633631,0.02015039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8754291,"threshold_uncertainty_score":0.3364549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02589605435681262,"score_gpt":0.2881361588825451,"score_spread":0.2622401045257324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}