{"id":"W2094327414","doi":"10.1021/ja074717z","title":"A Combinatorial Method for Solution-Phase Synthesis of Labeled Bivalent β-Turn Mimics","year":2007,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institute of General Medical Sciences; National Institute of Mental Health","keywords":"Chemistry; Combinatorial chemistry; Cycloaddition; Side chain; Monomer; Fluorescence; Amino acid; Click chemistry; Alkyne; Stereochemistry; Organic chemistry; Polymer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000653246,0.00014433,0.0004361081,0.000009096941,0.0001045213,0.00001061785,0.0005415718,0.0001012894,0.00003755377],"category_scores_gemma":[0.000643265,0.0001068966,0.0009500114,0.000257271,0.0003152362,0.00003234439,0.00008792416,0.0003628615,3.526078e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001876892,"about_ca_system_score_gemma":0.00009716787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001570625,"about_ca_topic_score_gemma":2.733233e-7,"domain_scores_codex":[0.9986175,0.00001481253,0.0006481279,0.000145251,0.000317865,0.0002564226],"domain_scores_gemma":[0.9965851,0.001371151,0.001355199,0.0002987476,0.0002601076,0.0001297212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002423612,0.0005368189,0.00009077843,0.00008172468,0.0001957946,4.278128e-7,0.0001096161,0.00000371829,0.989382,0.0001141858,0.004883445,0.004359155],"study_design_scores_gemma":[0.001157948,0.00002729292,0.00001071933,0.0000548087,0.0002228824,0.00003547026,0.000406095,0.000352905,0.9897875,0.001092276,0.006734995,0.0001170645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877464,0.00005128889,0.009970898,0.001716535,0.00009266069,0.00006593556,0.0000810916,0.00001248637,0.0002627692],"genre_scores_gemma":[0.9696108,0.00003831959,0.02946499,0.0001720209,0.0006336396,0.00001013021,0.000003141637,0.00001939033,0.00004754199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01949409,"threshold_uncertainty_score":0.4359119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741511294841068,"score_gpt":0.3358970645992049,"score_spread":0.3184819516507942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}