{"id":"W2094331928","doi":"10.1097/00007890-200407271-01122","title":"DIFFERENCES IN PHARMACOKINETIC PROFILES BETWEEN LONG-TERM HEART TRANSPLANT PATIENTS RECEIVING EITHER TACROLIMUS OR CYCLOSPORINE MICROEMULSION AND MYCOPHENOLATE MOFETIL MAINTENANCE IMMUNOSUPPRESSION","year":2004,"lang":"en","type":"article","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Mycophenolic acid; Immunosuppression; Medicine; Tacrolimus; Heart transplantation; Pharmacokinetics; Therapeutic drug monitoring; Mycophenolate; Urology; Trough level; Ciclosporin; Pharmacology; Internal medicine; Heart failure; Gastroenterology; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000228085,0.0001225553,0.0002909781,0.0001793882,0.0002495975,0.0003266995,0.00009137228,0.0002135593,0.001274103],"category_scores_gemma":[0.0008892252,0.00007955124,0.0001950981,0.0001821694,0.0001772432,0.0002768264,0.0001827485,0.0002858069,0.000201638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002193385,"about_ca_system_score_gemma":0.0001272783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006419118,"about_ca_topic_score_gemma":0.0006506854,"domain_scores_codex":[0.9998528,0.00002730412,0.00001809832,0.00003711852,0.00003021668,0.00003442826],"domain_scores_gemma":[0.9994294,0.0001527703,0.0001469233,0.00002574081,0.00005273377,0.0001923166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004026559,0.0003278649,0.9648686,0.00003005401,0.00009851353,0.0008773187,0.0003976404,0.0002169956,0.017597,0.00004435168,0.0001059123,0.01140911],"study_design_scores_gemma":[0.00004606857,0.002432324,0.9948689,0.00000505691,0.00004127485,0.001131462,0.0001718966,0.0002034951,0.0007744337,0.00001574238,0.0003040584,0.000005379799],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996898,0.0001164486,0.00003557457,0.000006349534,0.000002048303,0.00000250565,0.00002588179,6.762168e-7,0.0001207105],"genre_scores_gemma":[0.9995639,0.00005821291,0.00003707479,0.00002125358,0.00000706708,0.00000619221,0.0001215225,7.364312e-7,0.0001840633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001274103,"threshold_uncertainty_score":0.004262328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01963663933837326,"score_gpt":0.2883403899964124,"score_spread":0.2687037506580391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}