{"id":"W2094335398","doi":"10.1074/jbc.m109385200","title":"X-ray Crystallographic Structures of the Escherichia coli Periplasmic Protein FhuD Bound to Hydroxamate-type Siderophores and the Antibiotic Albomycin","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Basic Energy Sciences; National Center for Research Resources; Brookhaven National Laboratory; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; U.S. Department of Energy; National Institutes of Health; National Science Foundation","keywords":"Siderophore; Periplasmic space; Escherichia coli; Binding site; Biology; Bacteria; Chemistry; Biochemistry; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001695782,0.0005643775,0.0004870182,0.0002685824,0.0005511078,0.0006130759,0.0006895104,0.000715929,0.001806626],"category_scores_gemma":[0.0003363185,0.0003209904,0.0002579907,0.0005666456,0.0002983749,0.0003167786,0.0001523872,0.001008395,0.0004141351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001195536,"about_ca_system_score_gemma":0.0004328429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007233215,"about_ca_topic_score_gemma":0.006256014,"domain_scores_codex":[0.9998999,0.00002045069,0.000005746704,0.00001339075,0.00004068024,0.00001988948],"domain_scores_gemma":[0.9998754,0.00003511814,0.00002289614,0.000005076419,0.00003632605,0.00002511337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004440449,0.001191585,0.0155181,0.001527939,0.0003327495,0.003889114,0.001480371,0.03497123,0.8893299,0.00533973,0.01229159,0.02968712],"study_design_scores_gemma":[0.001440486,0.001489769,0.1931248,0.0003798254,0.0006484924,0.00337748,0.002601985,0.2245414,0.4617021,0.002724231,0.107655,0.0003144947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837805,0.006105414,0.002521161,0.0005638343,0.00006851002,0.00003570084,0.001623189,0.000165696,0.005136074],"genre_scores_gemma":[0.9749684,0.004588668,0.005050102,0.0002447237,0.00003241628,0.00004526817,0.01078346,0.00007002825,0.004216854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007233215,"threshold_uncertainty_score":0.01438218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009936647152140838,"score_gpt":0.2049826652544267,"score_spread":0.1950460181022859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}