{"id":"W2094468847","doi":"10.1021/ac0521955","title":"Label-Free Electrochemical Detection of Protein Based on a Ferrocene-Bearing Cationic Polythiophene and Aptamer","year":2006,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Aptamer; Polythiophene; Detection limit; Ferrocene; Cationic polymerization; Oligonucleotide; Combinatorial chemistry; Biosensor; Electrochemistry; Nuclease; Electrode; Chromatography; Conductive polymer; Enzyme; Polymer chemistry; Biochemistry; DNA; Physical chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000859939,0.0001511657,0.0001642338,0.00002799936,0.00004897017,0.00001294936,0.0001098756,0.0001997842,0.000002828078],"category_scores_gemma":[0.0001370297,0.0001411514,0.00007733218,0.0001484887,0.0001339358,0.000002517443,0.00005222882,0.0001309989,4.404449e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002603974,"about_ca_system_score_gemma":0.00003697177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002225958,"about_ca_topic_score_gemma":0.000008857276,"domain_scores_codex":[0.9990727,0.00001401731,0.0002156171,0.000347593,0.0001563109,0.0001937061],"domain_scores_gemma":[0.9993947,0.00001224177,0.00008392839,0.0003638152,0.00008770628,0.0000576083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009356741,0.00009330353,0.0002229135,0.00003374194,0.00001927673,0.000001014312,4.317065e-7,0.00000530033,0.9990444,0.00003039455,0.00003059458,0.0004250217],"study_design_scores_gemma":[0.0003486993,0.0001063691,0.0002367897,0.00002615778,0.00004315306,0.000006318746,0.000003522406,0.003111389,0.9954156,0.0003178237,0.0002248375,0.0001593815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937503,0.0001056501,0.0039099,0.00017662,0.000003416535,0.00007070078,0.00000555749,0.00003126713,0.001946536],"genre_scores_gemma":[0.9976618,0.000009206165,0.001596059,0.00006833094,0.0001129712,0.00000809197,0.00005700516,0.00001500136,0.0004714893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003911493,"threshold_uncertainty_score":0.5755988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005162324960504197,"score_gpt":0.2325684962331999,"score_spread":0.2274061712726957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}