{"id":"W2094468847","doi":"10.1021/ac0521955","title":"Label-Free Electrochemical Detection of Protein Based on a Ferrocene-Bearing Cationic Polythiophene and Aptamer","year":2006,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Aptamer; Polythiophene; Detection limit; Ferrocene; Cationic polymerization; Oligonucleotide; Combinatorial chemistry; Biosensor; Electrochemistry; Nuclease; Electrode; Chromatography; Conductive polymer; Enzyme; Polymer chemistry; Biochemistry; DNA; Physical chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004397033,0.0007603111,0.0006539635,0.0004805129,0.0002341526,0.0004933169,0.001281921,0.001545941,0.001207473],"category_scores_gemma":[0.001009289,0.000508423,0.0002363268,0.0003321179,0.0005589856,0.0006362397,0.0006086027,0.001424242,0.0006153935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005308573,"about_ca_system_score_gemma":0.0003345569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004570666,"about_ca_topic_score_gemma":0.0009762918,"domain_scores_codex":[0.9991068,0.000124654,0.00004134787,0.000207029,0.0004324581,0.00008772698],"domain_scores_gemma":[0.9993715,0.0002548413,0.00009739834,0.00006293909,0.000116048,0.00009724576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004500677,0.00002503953,0.00005228983,0.00006741648,0.00000611479,0.00005233263,0.00001625707,0.00005342785,0.9953121,0.0001422058,0.00007835946,0.004149425],"study_design_scores_gemma":[0.00001666382,0.00006446568,0.0004203109,0.000003634526,0.000007164239,0.0002211588,0.000004982612,0.001426828,0.996822,0.0000608388,0.0009409473,0.00001112493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5240062,0.006451141,0.4621128,0.0009241869,0.000601233,0.0003987318,0.0004961109,0.001921646,0.003088026],"genre_scores_gemma":[0.6600621,0.002204856,0.3249861,0.000555444,0.0001342201,0.0003500594,0.0004475878,0.0001273944,0.01113223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001545941,"threshold_uncertainty_score":0.004039407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005162324960504197,"score_gpt":0.2325684962331999,"score_spread":0.2274061712726957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}