{"id":"W2094497330","doi":"10.1074/jbc.m710092200","title":"Oxysterol and Diabetes Activate STAT3 and Control Endothelial Expression of Profilin-1 via OSBP1","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Dalhousie University","keywords":"Diabetes mellitus; Oxysterol; Cell biology; Internal medicine; Endocrinology; Chemistry; Biology; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001028121,0.000266517,0.0001578045,0.0001926933,0.0001147942,0.0002287731,0.000101133,0.0001503625,0.001623883],"category_scores_gemma":[0.00005187895,0.0001258235,0.0002777115,0.0001331884,0.0001512652,0.00013686,0.0001816235,0.0003859333,0.0003037439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002521398,"about_ca_system_score_gemma":0.0001669402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005497474,"about_ca_topic_score_gemma":0.001007035,"domain_scores_codex":[0.9998969,0.00001558032,0.000007107969,0.00002145121,0.00002001157,0.00003892735],"domain_scores_gemma":[0.9999447,0.000004546082,0.00002068057,0.000004036111,0.000006502367,0.00001957246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000631484,0.00003501912,0.001183238,0.0000612031,0.00001082859,0.00008294778,0.00002745017,0.00008493475,0.9945537,0.0002072895,0.00007850312,0.003043473],"study_design_scores_gemma":[0.0001761933,0.000974772,0.1364445,0.00003514563,0.00009888234,0.0008278283,0.0002799387,0.003560337,0.8476688,0.0005774678,0.009331579,0.00002442154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912887,0.003438606,0.002614378,0.0001232439,0.00004241935,0.00001820646,0.0005440199,0.00006025406,0.001870248],"genre_scores_gemma":[0.9950997,0.001159219,0.0008727445,0.00008671486,0.00001196939,0.00002191103,0.000469244,0.00001022801,0.002268204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001623883,"threshold_uncertainty_score":0.005432367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02388899790345757,"score_gpt":0.2527696452110189,"score_spread":0.2288806473075613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}