{"id":"W2094522927","doi":"10.1086/321281","title":"A Genome Screen of Families with Multiple Cases of Prostate Cancer: Evidence of Genetic Heterogeneity","year":2001,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Prostate cancer; Linkage (software); Genetic linkage; Allele; Genetics; Biology; Cancer; Genetic heterogeneity; Allele frequency; Gene; Oncology; Medicine; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006908851,0.001231775,0.0008217671,0.005024464,0.001977898,0.000935082,0.001116701,0.001381279,0.004405382],"category_scores_gemma":[0.004998961,0.0006276752,0.00104166,0.002620712,0.0009445587,0.0005150972,0.001110881,0.00083932,0.0003500211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005386724,"about_ca_system_score_gemma":0.0006225298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009198873,"about_ca_topic_score_gemma":0.006159463,"domain_scores_codex":[0.9984187,0.0004504613,0.0001081631,0.0004317162,0.000334067,0.0002568653],"domain_scores_gemma":[0.9971276,0.001492482,0.0005076368,0.0001827949,0.0001881401,0.000501254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001187166,0.0002704981,0.9299413,0.00004173089,0.0004879434,0.03521504,0.001196322,0.0002682843,0.02464389,0.0004029916,0.000553499,0.005791276],"study_design_scores_gemma":[0.00008456709,0.0003752124,0.907733,0.00002476766,0.0005421145,0.08463452,0.000800723,0.0007871098,0.003840715,0.0002785971,0.0008608247,0.00003788427],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984275,0.0002059139,0.000254187,0.0001654566,0.000006346937,0.000009868569,0.0002149841,0.00001501715,0.0007007924],"genre_scores_gemma":[0.9992794,0.00009167759,0.0002725002,0.00005370157,0.00001296222,0.000006194718,0.0001259706,0.000006977873,0.0001505169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009198873,"threshold_uncertainty_score":0.01829064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02741564047133228,"score_gpt":0.3069287610019605,"score_spread":0.2795131205306283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}