{"id":"W2094534564","doi":"10.1210/jc.2014-2118","title":"Activin A, B, and AB Increase Human Trophoblast Cell Invasion by Up-regulating N-Cadherin","year":2014,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Cytotrophoblast; Activin type 2 receptors; Trophoblast; Biology; Cadherin; Small interfering RNA; Gene knockdown; Cell biology; Activin receptor; Gene isoform; Smad2 Protein; Cell culture; Cell migration; Endocrinology; Internal medicine; Transfection; Cell; Signal transduction; Transforming growth factor; TGF beta signaling pathway; Transforming growth factor beta; Placenta; Gene; Fetus; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001337809,0.0002156336,0.0005644265,0.00005242705,0.0001842053,0.00002205171,0.0004919371,0.0001828276,0.00003911058],"category_scores_gemma":[0.001194901,0.0001491018,0.0002225948,0.00005282831,0.0004493668,0.00001198143,0.0002637635,0.0005348444,0.000007335467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000478286,"about_ca_system_score_gemma":0.00008663374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003183643,"about_ca_topic_score_gemma":0.000009048087,"domain_scores_codex":[0.9969687,0.001194673,0.001034788,0.0002532953,0.0002052616,0.0003432549],"domain_scores_gemma":[0.9979072,0.0004628637,0.0008509095,0.0004139447,0.0001340986,0.0002310506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007466654,0.0002515607,0.004262766,0.00001616316,0.0001439759,0.000003554865,0.00004873919,0.00004764872,0.97567,0.00008625395,0.004899073,0.01382357],"study_design_scores_gemma":[0.006502195,0.001195163,0.05539462,0.00004456901,0.0004870415,0.0002834374,0.0001481746,0.00005671228,0.7480882,0.0005415385,0.1868688,0.0003895483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942972,0.004275449,0.0004487626,0.0002754899,0.0003881984,0.00008626084,0.000005365054,0.000008967549,0.0002143179],"genre_scores_gemma":[0.9965025,0.0008460774,0.0004194877,0.0006107386,0.001229041,0.000002552603,0.000007485726,0.00003030411,0.0003518684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2275819,"threshold_uncertainty_score":0.6080196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02021357078787875,"score_gpt":0.3207564238568966,"score_spread":0.3005428530690178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}