{"id":"W2094534564","doi":"10.1210/jc.2014-2118","title":"Activin A, B, and AB Increase Human Trophoblast Cell Invasion by Up-regulating N-Cadherin","year":2014,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Cytotrophoblast; Activin type 2 receptors; Trophoblast; Biology; Cadherin; Small interfering RNA; Gene knockdown; Cell biology; Activin receptor; Gene isoform; Smad2 Protein; Cell culture; Cell migration; Endocrinology; Internal medicine; Transfection; Cell; Signal transduction; Transforming growth factor; TGF beta signaling pathway; Transforming growth factor beta; Placenta; Gene; Fetus; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000137085,0.0003081382,0.0001463742,0.0002895358,0.0001130474,0.0002766199,0.00008886212,0.0001749269,0.001987601],"category_scores_gemma":[0.0001624598,0.0001107671,0.0002141116,0.000137807,0.0001836861,0.0001393533,0.0001791596,0.0004500176,0.0004048933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001959564,"about_ca_system_score_gemma":0.0002045438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008123139,"about_ca_topic_score_gemma":0.001091459,"domain_scores_codex":[0.9998823,0.00002290328,0.00001421164,0.00001801077,0.00003324155,0.00002931454],"domain_scores_gemma":[0.9998888,0.00003724258,0.00002280748,0.00001364942,0.000009134088,0.00002834655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002822753,0.00008161757,0.0002348974,0.00003833505,0.000005223003,0.00004660281,0.00002037505,0.00005235005,0.9971617,0.00003269967,0.0000694397,0.001974413],"study_design_scores_gemma":[0.0000864606,0.001304982,0.01157768,0.00001497869,0.00003782905,0.0002976232,0.00006762009,0.001221044,0.9811718,0.00004900137,0.004166893,0.000004098118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917379,0.003004684,0.001390095,0.0001298789,0.00003880406,0.00003818137,0.0002953295,0.00008308871,0.003282204],"genre_scores_gemma":[0.9907687,0.002320951,0.002442073,0.00008356357,0.00002463613,0.00007155292,0.0005513266,0.00001727681,0.003719791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001987601,"threshold_uncertainty_score":0.006649196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02021357078787875,"score_gpt":0.3207564238568966,"score_spread":0.3005428530690178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}