{"id":"W2094538082","doi":"10.1016/j.micinf.2005.11.009","title":"CR3 (CD11b/CD18) is the major macrophage receptor for IgM antibody-mediated phagocytosis of African trypanosomes: Diverse effect on subsequent synthesis of tumor necrosis factor α and nitric oxide","year":2006,"lang":"en","type":"article","venue":"Microbes and Infection","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Food Inspection Agency; University of Saskatchewan","funders":"University of Saskatchewan","keywords":"Phagocytosis; Biology; Macrophage; Opsonin; Antibody; Tumor necrosis factor alpha; Integrin alpha M; Microbiology; Antibody opsonization; Complement receptor; Receptor; Immunoglobulin M; Immunology; Immune system; Immunoglobulin G; Complement system; Molecular biology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002040827,0.0003698119,0.0002663009,0.0002500339,0.0002410541,0.0002939742,0.0001998678,0.0003133878,0.001184494],"category_scores_gemma":[0.0002066986,0.0001633801,0.0002806848,0.0001428688,0.000201288,0.0002057699,0.0002805588,0.0005032017,0.0002496228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003362914,"about_ca_system_score_gemma":0.0002162968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008373157,"about_ca_topic_score_gemma":0.001041776,"domain_scores_codex":[0.9998337,0.00003729327,0.000009577485,0.00002506815,0.00002928271,0.00006501128],"domain_scores_gemma":[0.9998667,0.00001797541,0.00003814841,0.000007652622,0.00002570636,0.00004379907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002727081,0.00001327998,0.0003636099,0.00003741304,0.000005933281,0.00007738003,0.00001441436,0.00002238505,0.9963445,0.0001359423,0.00003768437,0.002674713],"study_design_scores_gemma":[0.00005381734,0.0005647078,0.02088775,0.00002459097,0.00004898942,0.001185427,0.00008699966,0.0006387899,0.9714776,0.0002393953,0.004781077,0.00001087005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842961,0.009360955,0.003914303,0.0002244262,0.00005502025,0.00003272869,0.0001358744,0.00003917604,0.001941489],"genre_scores_gemma":[0.9923563,0.002848393,0.002293512,0.000116944,0.00003031102,0.00002082116,0.0001982038,0.00001362225,0.002121971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001184494,"threshold_uncertainty_score":0.003962517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01313220937669394,"score_gpt":0.2728947979690156,"score_spread":0.2597625885923217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}