{"id":"W2094538082","doi":"10.1016/j.micinf.2005.11.009","title":"CR3 (CD11b/CD18) is the major macrophage receptor for IgM antibody-mediated phagocytosis of African trypanosomes: Diverse effect on subsequent synthesis of tumor necrosis factor α and nitric oxide","year":2006,"lang":"en","type":"article","venue":"Microbes and Infection","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Food Inspection Agency; University of Saskatchewan","funders":"University of Saskatchewan","keywords":"Phagocytosis; Biology; Macrophage; Opsonin; Antibody; Tumor necrosis factor alpha; Integrin alpha M; Microbiology; Antibody opsonization; Complement receptor; Receptor; Immunoglobulin M; Immunology; Immune system; Immunoglobulin G; Complement system; Molecular biology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005251934,0.0002055744,0.0004187672,0.0002652056,0.0002122881,0.00003616551,0.00006806695,0.00009050161,0.0001321917],"category_scores_gemma":[0.0003229784,0.0001381223,0.0001748985,0.0004329548,0.0002582278,0.00009599696,0.00004721805,0.0001338542,0.000008188022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008603971,"about_ca_system_score_gemma":0.00004070971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002082302,"about_ca_topic_score_gemma":0.00005658037,"domain_scores_codex":[0.9987972,0.00008331008,0.0003510185,0.0002977025,0.000186498,0.0002843146],"domain_scores_gemma":[0.9986539,0.0006215356,0.0001963632,0.0002615567,0.0001615038,0.0001050996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004151427,0.0002443128,0.0403603,0.0003973561,0.0001062809,9.436877e-7,0.00006213865,3.660765e-7,0.9531882,0.00004088935,0.001884281,0.003299794],"study_design_scores_gemma":[0.0008838034,0.0006108502,0.4638881,0.00008589773,0.0001165606,0.00001411098,0.00005013821,0.00002313762,0.5316156,0.00001097781,0.002619896,0.00008091381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967241,0.0004446798,0.00009975921,0.0004389282,0.00004222603,0.001117842,0.0009356386,0.00003113875,0.0001657385],"genre_scores_gemma":[0.9986442,0.0006539268,0.0001382754,0.00007069713,0.00006773392,0.0001257478,0.00007697802,0.00002510125,0.0001973722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4235278,"threshold_uncertainty_score":0.5632464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01313220937669394,"score_gpt":0.2728947979690156,"score_spread":0.2597625885923217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}