{"id":"W2094544734","doi":"10.1111/j.1471-4159.2009.06524.x","title":"Reductions of acetylcholine release and nerve growth factor expression are correlated with memory impairment induced by interleukin‐1β administrations: effects of omega‐3 fatty acid EPA treatment","year":2009,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"Canadian Institutes of Health Research; Amarin Corporation","keywords":"Acetylcholine; Nerve growth factor; Endocrinology; Cholinergic; Internal medicine; Neurotrophic factors; Brain-derived neurotrophic factor; Glucocorticoid; Hippocampal formation; Neurotrophin; Antagonist; Hippocampus; Receptor antagonist; Chemistry; Psychology; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005394479,0.000243685,0.0003659552,0.000121227,0.00009752129,0.00003348027,0.0001761965,0.00008991747,0.00002047553],"category_scores_gemma":[0.0004309612,0.0001880777,0.0001121696,0.0002382512,0.00007042084,0.0002694476,0.00002301204,0.0002943597,6.491413e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004825563,"about_ca_system_score_gemma":0.0001236685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":8.662731e-7,"about_ca_topic_score_gemma":2.457051e-7,"domain_scores_codex":[0.9982879,0.0001442136,0.0007073074,0.0002983492,0.0004047415,0.0001575012],"domain_scores_gemma":[0.9979617,0.0001442007,0.001225146,0.0002488728,0.0002042454,0.0002158584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004016325,0.0006080467,0.00003401066,0.00006489464,0.000009499279,0.0001008089,0.0001765344,0.00002779007,0.9981472,0.000008818944,0.0001091788,0.0003115636],"study_design_scores_gemma":[0.002076081,0.002695713,0.001167819,0.0002096002,0.0000525412,0.00065648,0.00008148917,0.00005961688,0.9928325,0.00002421392,0.00001178279,0.0001320939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998723,0.00005953647,0.0001967813,0.0005336553,0.0001639376,0.0002460373,0.00002680445,0.00001873649,0.00003152799],"genre_scores_gemma":[0.9992861,0.0001988626,0.0002122806,0.0001231277,0.00005907738,0.000006083977,0.000004131917,0.00001734096,0.0000930518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005314652,"threshold_uncertainty_score":0.7669584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01647733211956571,"score_gpt":0.2531096694876382,"score_spread":0.2366323373680725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}