{"id":"W2094729320","doi":"10.1074/jbc.m401221200","title":"The Specificities of Four Yeast Dihydrouridine Synthases for Cytoplasmic tRNAs","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health; Canadian Institutes of Health Research; University of Miami","keywords":"Cytoplasm; Yeast; Transfer RNA; Cell biology; Biology; Biochemistry; Chemistry; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001704711,0.0004337599,0.0003570828,0.0004504098,0.0001415141,0.0004375444,0.0002555699,0.0003433152,0.0008295192],"category_scores_gemma":[0.0004291727,0.00030481,0.0003083881,0.0002679706,0.0002885244,0.0001761538,0.0002976487,0.0003711041,0.0004128709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000407892,"about_ca_system_score_gemma":0.0001939359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008291861,"about_ca_topic_score_gemma":0.001101556,"domain_scores_codex":[0.9997306,0.00004043516,0.00003047168,0.0001026782,0.0000624313,0.00003328822],"domain_scores_gemma":[0.9996709,0.00008980693,0.00005618409,0.00003708979,0.00007121718,0.00007490029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005306977,0.000004668904,0.0005090686,0.00002283338,0.000002829501,0.00001324773,0.00001149095,0.00003300552,0.9979646,0.0000437547,0.000009647227,0.001331792],"study_design_scores_gemma":[0.000006938893,0.00009726489,0.01179472,0.000005967437,0.00001751525,0.0003024442,0.00003954814,0.0006618148,0.9855214,0.00005797178,0.001484473,0.00000999495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906262,0.002055474,0.005290675,0.00009861186,0.00002238442,0.00002687171,0.0005340919,0.0001519433,0.001193674],"genre_scores_gemma":[0.9895799,0.000721317,0.006735379,0.00005865174,0.000006043139,0.00003270285,0.001401213,0.00003180054,0.001433094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008295192,"threshold_uncertainty_score":0.00295943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03205860182439435,"score_gpt":0.2607616296687183,"score_spread":0.2287030278443239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}