{"id":"W2094729803","doi":"10.3791/2763","title":"DNA Extraction from Paraffin Embedded Material for Genetic and Epigenetic Analyses","year":2011,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Occupational Cancer Research Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"DNA extraction; Lysis buffer; DNA microarray; DNA; Biology; Proteinase K; Nucleic acid; Lysis; Epigenetics; DNA methylation; Sodium dodecyl sulfate; Molecular biology; Polymerase chain reaction; Chromatography; Gene; Chemistry; Biochemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009190213,0.000124372,0.0001880043,0.00004942764,0.00005459131,0.00001715528,0.0001293666,0.0001339834,0.00007623381],"category_scores_gemma":[0.00002276406,0.0001079739,0.0001084945,0.00003092959,0.00005079801,0.000004617758,0.0000394462,0.00003817096,8.578924e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008107829,"about_ca_system_score_gemma":0.00002738077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002153539,"about_ca_topic_score_gemma":0.000001611811,"domain_scores_codex":[0.9991953,0.00006058654,0.0003565597,0.0001843129,0.00007250882,0.000130779],"domain_scores_gemma":[0.9993684,0.000008013522,0.0002948156,0.0001641253,0.00008654353,0.00007814542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003725315,0.0001249505,0.0002381711,0.000002940479,0.0001210055,0.000002516477,0.00008565084,8.660657e-7,0.997481,0.0000241037,0.0004944012,0.001051896],"study_design_scores_gemma":[0.0008054053,0.0005680616,0.002410604,0.000009359465,0.0000705641,0.00002881382,0.00007717396,0.00002138464,0.9919007,0.0004315219,0.003559448,0.0001169239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9223064,0.001070646,0.07621166,0.0000097618,0.0001218578,0.0001871513,0.00002404084,0.000005729699,0.00006278375],"genre_scores_gemma":[0.8995689,0.0003867574,0.09959824,0.00009758331,0.000197573,0.00004852175,0.00005323027,0.00001861941,0.00003059535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02338657,"threshold_uncertainty_score":0.4403049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06171041381074732,"score_gpt":0.4589322119794625,"score_spread":0.3972217981687152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}