{"id":"W2094747616","doi":"10.1074/jbc.m113.534701","title":"PTPN14 Forms a Complex with Kibra and LATS1 Proteins and Negatively Regulates the YAP Oncogenic Function","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Queen's University; Roswell Park Cancer Institute","keywords":"Hippo signaling pathway; Biology; Cell biology; Effector; Carcinogenesis; Cell growth; Kinase; Signal transduction; Gene knockdown; Cancer research; Cancer; Genetics; Cell culture","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001948497,0.0005255941,0.0003448321,0.0003648626,0.000349521,0.0003201932,0.0003540804,0.0003215671,0.002618319],"category_scores_gemma":[0.0002075369,0.0002906335,0.0004006143,0.0001805239,0.0001777758,0.0002270845,0.0005304994,0.0003781997,0.001017562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005638419,"about_ca_system_score_gemma":0.0003066916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005338048,"about_ca_topic_score_gemma":0.001004653,"domain_scores_codex":[0.9996189,0.00005879706,0.00003415789,0.00008454134,0.0001270713,0.00007648264],"domain_scores_gemma":[0.9998593,0.000008818001,0.000059306,0.0000104457,0.00002366942,0.00003832583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001700907,0.00002578868,0.002990529,0.0001221515,0.00006364792,0.0003487098,0.00002720832,0.0001181489,0.9927896,0.000184476,0.0002765206,0.002883176],"study_design_scores_gemma":[0.00006971152,0.0002149969,0.09223652,0.00002695676,0.00009115051,0.004117089,0.000105542,0.006692188,0.8792201,0.0002711568,0.01693167,0.00002287387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897947,0.003823248,0.00393407,0.00019217,0.00004761775,0.00002847717,0.000323405,0.0001332795,0.001722911],"genre_scores_gemma":[0.9906366,0.001118032,0.001630281,0.0000594028,0.00001807734,0.00003597276,0.001291953,0.00001908201,0.005190547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002618319,"threshold_uncertainty_score":0.008759141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01786208500687016,"score_gpt":0.2193103681609304,"score_spread":0.2014482831540603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}