{"id":"W2094774273","doi":"10.1007/s00401-013-1159-9","title":"Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response","year":2013,"lang":"en","type":"article","venue":"Acta Neuropathologica","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Chongqing University of Arts and Sciences","keywords":"Experimental autoimmune encephalomyelitis; Immunology; Multiple sclerosis; Autoimmune disease; Immune system; T cell; Autoimmunity; CD8; Biology; Demyelinating disease; Medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000420382,0.0005798929,0.0004668761,0.0005972406,0.0003233264,0.0006329281,0.0002818865,0.0005432257,0.002431024],"category_scores_gemma":[0.0004525813,0.000222805,0.0002692111,0.0001978055,0.0005136671,0.0004417097,0.0003091278,0.001855066,0.001090828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003211351,"about_ca_system_score_gemma":0.0002993163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003030248,"about_ca_topic_score_gemma":0.0005254584,"domain_scores_codex":[0.9994672,0.00009239258,0.00005749131,0.0001240896,0.0001071601,0.0001516952],"domain_scores_gemma":[0.9990426,0.000230037,0.0001728693,0.0001877353,0.0001126596,0.0002540655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002584752,0.0001404026,0.0009351627,0.00002977718,0.000007763458,0.000166545,0.00004307284,0.00004799644,0.9965746,0.0002842618,0.00007731366,0.001434568],"study_design_scores_gemma":[0.0001831546,0.002026662,0.01354592,0.00002883657,0.00004947719,0.002809216,0.0002179483,0.001424731,0.9752386,0.000684527,0.003777142,0.00001381881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967352,0.0003591675,0.0006278468,0.00008881544,0.0000518299,0.00001961011,0.0001489198,0.00008689847,0.001881812],"genre_scores_gemma":[0.996094,0.000136664,0.0005824219,0.00008216721,0.00003567936,0.000028393,0.0001882073,0.00004178882,0.002810708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002431024,"threshold_uncertainty_score":0.008132637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03259161933719636,"score_gpt":0.2510695790258153,"score_spread":0.2184779596886189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}