{"id":"W2094817439","doi":"10.1097/01.lab.0000020417.13757.05","title":"CCR3-Blocking Antibody Inhibits Allergen-Induced Eosinophil Recruitment in Human Skin Xenografts from Allergic Patients","year":2002,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Christie (Canada)","funders":"","keywords":"Immunology; Eosinophil; CCR3; Peripheral blood mononuclear cell; Basophil; Blocking antibody; Allergic inflammation; Medicine; Chemokine; In vivo; Cytokine; Humanized mouse; Antibody; Allergy; Chemokine receptor; Inflammation; Biology; Immune system; Immunoglobulin E; In vitro; Asthma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001469534,0.0003214741,0.0003812544,0.0002887612,0.0002333227,0.0000565315,0.0001202091,0.000236406,0.0003323422],"category_scores_gemma":[0.0001096449,0.0003106966,0.00008105543,0.0007420033,0.000136326,0.0002899073,0.00005075962,0.0002970721,0.0001312716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002006258,"about_ca_system_score_gemma":0.0001278693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009240054,"about_ca_topic_score_gemma":0.00008079412,"domain_scores_codex":[0.9976733,0.0002256131,0.0006290462,0.0005451627,0.0005533902,0.0003735274],"domain_scores_gemma":[0.9986392,0.00003229361,0.0002482928,0.000421791,0.0002564639,0.0004020042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006107016,0.001266454,0.5903336,0.0001075165,0.00009963002,0.0001192815,0.003543901,0.00005981818,0.3946773,0.00009893595,0.003191017,0.006441379],"study_design_scores_gemma":[0.005541067,0.0007252704,0.8654383,0.0007701003,0.00009411883,0.000001169674,0.0002757137,0.0004764137,0.1081775,0.0002245663,0.01764822,0.0006275315],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997082,0.0007358613,0.000002231136,0.0003333901,0.0003339317,0.0009673624,0.00005345347,0.0001385333,0.0003532715],"genre_scores_gemma":[0.9967864,0.00003397009,0.0001573932,0.00183208,0.0004085563,0.0001027625,0.0005590799,0.00005470825,0.00006501878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2864998,"threshold_uncertainty_score":0.9999345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05157275582922851,"score_gpt":0.2961179522956583,"score_spread":0.2445451964664298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}