{"id":"W2094980526","doi":"10.1016/j.bbrc.2007.12.129","title":"Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2","year":2008,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":151,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"STIM1; EF hand; Endoplasmic reticulum; Circular dichroism; Chemistry; Calcium-binding protein; Biophysics; Crystallography; Biology; Biochemistry; Calcium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0001738505,0.0001041473,0.0002018337,0.00006195718,0.0005536989,0.00002283361,0.0003448136,0.00008914911,0.000001995813],"category_scores_gemma":[0.0004616574,0.00006894716,0.00004720632,0.0003990569,0.004659211,0.00007361521,0.0006198024,0.000336631,9.663329e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001353911,"about_ca_system_score_gemma":0.00004793387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004402805,"about_ca_topic_score_gemma":8.340176e-7,"domain_scores_codex":[0.9986397,0.0003460156,0.0002215349,0.0002559617,0.0003342934,0.0002024827],"domain_scores_gemma":[0.9984331,0.0007954399,0.0000895188,0.0004170084,0.0001434553,0.0001214778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005678164,0.000178984,0.0001432717,0.00003726044,0.00000433415,7.42201e-7,0.000498813,5.914704e-8,0.9944974,0.003749751,0.00003724364,0.000795373],"study_design_scores_gemma":[0.0003058274,0.0001584293,0.006005843,0.00007980821,0.000006566904,0.00001959156,0.0001215149,0.0008967235,0.9912767,0.0006660295,0.0003733336,0.00008957142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972754,0.0001137353,0.00003042647,0.00218188,0.00002026976,0.0002339668,0.00004095546,0.000009589876,0.00009382772],"genre_scores_gemma":[0.997847,0.001823325,0.0001144079,0.00004091356,0.00004956482,0.00001444645,0.000008508681,0.000008515329,0.00009330555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005862571,"threshold_uncertainty_score":0.9980496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1420317790034808,"score_gpt":0.3458551214923661,"score_spread":0.2038233424888853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}