{"id":"W2094988852","doi":"10.1074/mcp.m114.040113","title":"Targeting Synaptic Pathology with a Novel Affinity Mass Spectrometry Approach","year":2014,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Demensfonden; Swedish Brain Power","keywords":"Synaptic membrane; Neuroscience; Proteomics; Chemistry; Membrane protein; Function (biology); Biology; Cell biology; Biochemistry; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003917123,0.0008188928,0.0005393925,0.0007324939,0.0005196307,0.0007975971,0.001068837,0.001024364,0.0009677689],"category_scores_gemma":[0.0002876055,0.0005381177,0.0004618862,0.0002973889,0.0003753361,0.0006191966,0.0007413719,0.001259897,0.0009809218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005328722,"about_ca_system_score_gemma":0.0004058257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001151462,"about_ca_topic_score_gemma":0.002756741,"domain_scores_codex":[0.999537,0.00003939814,0.00002901133,0.0001163675,0.0002087322,0.00006960929],"domain_scores_gemma":[0.999731,0.00005040182,0.00005863521,0.00004457904,0.00007291295,0.00004241123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001388436,0.00001460368,0.00007872039,0.00001855038,0.00000963748,0.0000256789,0.000006153333,0.0000247214,0.9982482,0.00009381831,0.00006472497,0.001401234],"study_design_scores_gemma":[0.00001425356,0.0001083488,0.001985326,0.000004528499,0.00003080466,0.0009305369,0.00001575999,0.00296243,0.9904241,0.0002319819,0.003266696,0.00002515203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5183272,0.004593628,0.4676193,0.001635251,0.0003181648,0.0003578958,0.0008860502,0.00186982,0.004392764],"genre_scores_gemma":[0.6758352,0.003173589,0.3114793,0.001198935,0.0001339365,0.0003359561,0.0008867935,0.0001634555,0.006792789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001151462,"threshold_uncertainty_score":0.003866255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02312410126833473,"score_gpt":0.2552496526686002,"score_spread":0.2321255514002654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}