{"id":"W2094988852","doi":"10.1074/mcp.m114.040113","title":"Targeting Synaptic Pathology with a Novel Affinity Mass Spectrometry Approach","year":2014,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Demensfonden; Swedish Brain Power","keywords":"Synaptic membrane; Neuroscience; Proteomics; Chemistry; Membrane protein; Function (biology); Biology; Cell biology; Biochemistry; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000871513,0.0003673017,0.0003825541,0.0002990903,0.0003964063,0.0001349306,0.0009706964,0.0001610132,0.0000308851],"category_scores_gemma":[0.0009458073,0.0003208571,0.0001091895,0.001000712,0.0006573115,0.0001732308,0.0002915777,0.0009752975,0.00008369556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005510583,"about_ca_system_score_gemma":0.0001162636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002874834,"about_ca_topic_score_gemma":1.167069e-7,"domain_scores_codex":[0.9959158,0.000728016,0.0003300816,0.00131439,0.000654327,0.001057407],"domain_scores_gemma":[0.9986724,0.000181829,0.0001767511,0.0006464153,0.00006456321,0.0002580729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009603509,0.0002635838,0.0001131526,0.00004177192,0.000007406946,0.0007453545,0.00003868309,0.0009287752,0.9957573,0.001959052,0.00001170642,0.00003722212],"study_design_scores_gemma":[0.0009232403,0.0005656916,0.00002061434,0.000006487682,0.00002370952,0.0003158478,0.00001425328,0.02293639,0.9743823,0.0002893691,0.0001697905,0.0003522971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7003706,0.00001964807,0.2973682,0.0001954545,0.0001233568,0.0007610126,0.000007326775,0.0001197024,0.001034653],"genre_scores_gemma":[0.9774046,0.00001776116,0.02051871,0.001603017,0.00008400805,0.0001423413,0.000003161136,0.00008580156,0.0001406074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.277034,"threshold_uncertainty_score":0.9999244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02312410126833473,"score_gpt":0.2552496526686002,"score_spread":0.2321255514002654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}